| Objective: The purpose of this study was to investigate the value of echocardiographic parameters in the assessment and prediction of CoA.Methods:the relevant literatures about the diagnosis of coarctation by echocardiography were retrieved by computer from PubMed,web of science,geenmedical,the Cochrane Library,CMB,CNKI,Wanfang,and VIP from the establishment of the database to December 1,2019.According to the inclusion and exclusion criteria,two assessors independently selected and extracted the literature,and evaluated the quality of the literature by using the risk assessment criteria of Quadas-2 provided by Revman 5.3statistical software.Using Stata software to analyze the data that can be combined,the sensitivity(SEN),specificity(SPE),positive likelihood ratio(PLR),negative likelihood ratio(NLR),diagnostic ratio(DOR)were analyzed,and the published bias analysis of the included literature was carried out.Results: the mean mitral valve diameter Z score,ascending aorta Z score and diameter,catheter / isthmus diameter,and isthmus diameter Z score were all lower in 1373 patients with CoA(P <0.05),the PV diameter Z score and RV / LV(diameter,area)ratio were higher in fetus with CoA was higher(P >0.05).The parameters of postpartum ultrasound were carotid subclavian index,with a sensitivity of 0.90(95% CI: 0.72-0.97),a specificity of 0.97(95% CI: 0.92-0.99),a positive likelihood ratio of 26.7(95% CI: 10.7-66.5),a negative likelihood ratio of 0.10(95% CI: 0.03-0.32),a diagnostic ratio of 262(95%CI: 37-1875),and an area under the working characteristic curve(AUC)of 0.98.Conclusion: for the fetus at risk,the above echocardiographic parameters can accurately evaluate and predict CoA fetus before and after birth. |
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