| Objective:Through the application of erxian decoction combined with percutaneous kyphoplasty(PKP)in the treatment of postmenopausal osteoporosis vertebral compression fracture(liver and kidney deficiency type).Observing its clinical efficacy,and providing a clinical reference for the treatment of postmenopausal osteoporosis vertebral compression fracture with integrated traditional Chinese and western medicine.Methods: A total of 68 cases(liver and kidney deficiency type)of postmenopausal osteoporotic vertebral compression fracture diagnosed and treated by gansu provincial hospital of traditional Chinese medicine from October 2016 to April 2018 were selected.According to the random grouping method,the patients were divided into control group and experimental group,34 cases in each group,and both groups were treated with PKP surgery.All patients in the control group were given calcium carbonate D3 tablets orally after surgery,and were injected with calcitonin for anti-osteoporosis treatment.On the basis of the treatment in the control group,the patients in the experimental group were given erxian decoction orally from the second day after the operation,with one course of treatment for 6weeks.The patients in both groups received 4 courses of treatment.In preoperative,three days after operation,postoperative march and June record and compare the postoperative patients of TCM clinical syndrome integral,visual analogue scale(VAS)and Oswestry disability index(ODI)score,compared two groups of patients lumbar spine bone mineral density before and after treatment(BMD)of changes,observe two groups during the follow-up of patients with vertebral body fracture rates again,compare the clinical curative effect of two groups of patients after treatment,using SPSS22.0 software statistical analysis of clinical data.Results:1.Comparison of general clinical data:The two groups were all female patients,and there was no significant difference between the two groups in baseline data such as age,weight,height,lesion segment,and course of disease(P > 0.05).2.Total scores of TCM clinical symptoms(low back pain,systemic acid distress,lower limb weakness,leg cramps,fatigue)of the two groups were compared preoperatively,3 days after surgery,3 months after surgery and 6 months after surgery: intra-group and inter-group comparisons were performed preoperatively and 3 days after surgery,and the differences werenot statistically significant(P > 0.05).The clinical symptoms of TCM in the two groups were improved 3 months after surgery and 6 months after surgery,and the difference was statistically significant(P < 0.05).Comparison between the two groups 3 months after surgery and 6 months after surgery showed that the total score of TCM clinical symptoms in the experimental group decreased significantly(P < 0.05).3.Comparison of patients' VAS scores at preoperative and postoperative time points between the two groups: there was no statistically significant difference in the preoperative VAS scores between the two groups(P > 0.05);VAS scores of the patients in the two groups were significantly lower than those before the operation at 3 days after the operation,3months after the operation and 6 months after the operation at each time point during the follow-up,and the difference between the two groups was statistically significant(P <0.05).There was no significant difference in VAS scores between the two groups 3 days after surgery(P > 0.05).VAS scores were compared between the two groups 3 months and 6months after surgery,and the difference was statistically significant(P < 0.05).4.Comparison of ODI scores at each time point: there was no significant difference in ODI scores between the two groups before surgery(P > 0.05);The ODI scores of patients in the two groups were significantly lower at each time point after surgery than before,and the differences were statistically significant(P < 0.05).There was no significant difference in ODI scores between the two groups 3 days after surgery(P > 0.05).The ODI scores of patients in the two groups were compared between the two groups 3 months and 6 months after surgery,and the ODI scores in the experimental group decreased more significantly,and the differences were statistically significant(P < 0.05).5.Comparison of the incidence of vertebral refracture between the two groups during the follow-up period:All patients in both groups were followed up for 8 ~ 12 months after surgery,a total of 5 cases of adjacent vertebral fracture occurred in the control group,and a total of 1 case of adjacent vertebral fracture occurred in the experimental group.Comparison of the rate of vertebral refracture between the two groups showed that the experimental group was significantly lower than the control group,and the difference was statistically significant(P < 0.05).6.BMD value: BMD before treatment showed no significant difference between the twogroups(P > 0.05).The BMD values of the two groups were compared after treatment and before treatment,and the difference was statistically significant(P < 0.05).BMD values of the two groups after treatment were compared between the two groups,and the experimental group was superior to the control group,with statistically significant difference(P < 0.05).7.Comparison of clinical efficacy: at the last follow-up,the clinical efficacy of the two groups was evaluated.The total effective rate of the experimental group was better than that of the control group,and the difference between the two groups was statistically significant(P< 0.05).Conclusions:postmenopausal osteoporotic vertebral compression fractures patients(liver and kidney deficiency type),using two fairy soup combined PKP holds for clinical treatment,which can effectively improve the patient's clinical syndrome of traditional Chinese medicine,alleviate symptoms of pain and improve function obstacle,to reduce the rate of vertebral fracture again,and vertebral bone mineral density can be improved to some extent,the clinical curative effect is distinct,worthy of clinical application. |
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