Risk Factors Of In-hospital Death In 409 Patients With Acute Aortic Dissection

Objective The purpose of this study was to analyze the clinical features of patients with acute aortic dissection in the hospital and to explore the risk factors associated with death in hospital.Methods Retrospective analysis of clinical data of acute aortic dissection patients admitted to Ningxia Medical University General Hospital from January 1,2010 to January 1,2018,including general conditions,past history,main clinical symptoms,relevant test results,complications,prognosis,analysis of clinical features of patients with acute aortic dissection.Logistic regression was used to analyze the independent risk factors for in-hospital death in patients with acute aortic dissection according to the patients' in-hospital survival.Results 1.The mean age of acute aortic dissection was 52.22±11.36,336 males and 73 females.The male-female ratio was 4.6:1.Pain was the main clinical manifestation.Chest pain was the most common(41.8%)and 38 cases(9.3%)died in the hospital.2.The blood pressure,heart rate(29)100beats/min,platelet count<125*10^9/L,cholesterol,symptoms to admission time,Stanford classification,ascending aortic diameter,medium-large pericardial effusion,moderate to severe aortic regurgitation,renal insufficiency,heart failure and Surgical treatment were the influencing factor of in-hospital mortality in patients with acute aortic dissection.Heart rate(29)100 beats/min,platelet count level <125*10^9/L,symptoms onset to admission time,medium-large pericardial effusion,and heart failure were independent risk factors for in-hospital death in patients with acute aortic dissection.Conclusion 1.Heart rate(29)100 beats/min,platelet count level <125*10^9/L,symptom onset to admission,medium-large pericardial effusion,and heart failure were independent risk factors of in-hospital death in patients with acute aortic dissection.2.Establishing chest pain center,early identification of patients with high-risk chest pain,standardized diagnosis and treatment,can effectively reduce the in-hospital mortality of patients with acute aortic dissection.