Study On Clinical Efficacy Evaluation Of "xingnao Tiaofu" Acupuncturein Treating Insomnia After Stroke

Objective: To observe the difference in clinical efficacy between “Xingnao Tiaofu acupuncture”,common acupuncture and oral estazolam for the treatment of insomnia after stroke.Methods: 120 cases of post-stroke insomnia patients who were diagnosed in the Chinese and Western medicine were included in the study.They were randomly divided into Group A(“Xingnao Tiaofu” group),Group B(normal acupuncture group)and Group C(Western medicine treatment group).There are 40 cases in each group.The group A and B were treated once a day in the morning,5 times a week,rest on weekends,and 5 days as 1 course.A total of 4 courses of treatment were completed.Group C used oral estazolam tablets 1mg,1 time/day,taked it before went to bed every Monday to Friday,5 days as a course of treatment,4 courses of treatment were completed.The Pittsburgh Sleep Quality Index(PSQI),the Hamilton Depression Rating Scale(HAMD),the Hamilton Anxiety Scale(HAMA),and the neurological deficit score(NIHSS)are used to give scores among different groups and with in them for those who are admitted to the group before treatment,who have been treated for four months,and who are visited for 12 months.Then,evaluating the comprehensive effect of treatment respectively by using these three methods.Result:1.Overall efficacy: Full analysis set(FAS set): After 1 month of treatment,the effective rate of the group A was 95.00%(38/40),and the group B was 92.50%(37/40).87.50%(35/40)of the group C,there was no statistically significanct difference in total effective rate among the three groups,but the healing rate(healing and significant efficiency)of the group A was higher than that of the group B and the group C.Compared with the group B,the group A hadno obvious advantage in reducing the PSQI value,but it still had a significant advantage over the group C.Per-protocol set(PP set): After 1 month of treatment,the effective rate of group A was 94.59%(35/37),the group B was 92.11%(35/38),the group C was 86.11%(32/36),the total effective rate of the three groups was compared,the difference was not statistically significant(P>0.05),but the rate of recovery(recovery and significant efficiency)of the group A was significantly improved than that of the group B and the group C.The group A had no significant advantage in reducing the PSQI value compared with the group B,but it was still obviously better than the group C.2.Using the full analysis set(FAS set)and the compliance program set(PP set): There were significantly different in scale scores with the patients in three groups after 4 weeks of treatment with three methods(all P<0.01).The PSQI,HAMD and HAMA scores in the group A and the group B were significantly better than those in the group C(both P<0.01).The PSQI,HAMD and HAMA scores in the group A and the group B were improved,no significant difference(P>0.05);the improvement of NIHSS score in group A was significantly better than that in group B and group C(P<0.01).There was no significant difference in the improvement of NIHSS score between group B and group C(P>0.05).At the 12-week follow-up,the full analysis set(FAS set)and the compliance program set(PP set): the improvement of PSQI,HAMD,and HAMA scores in the group A and the group B were better than those in the group C(all P<0.01).There were no significant differences in PSQI,HAMD and HAMA scores between the group A and the group B(P>0.05).The improvement of NIHSS score in the group A was significantly better than that of the group B and the group C(both P<0.01),there was no significant difference in the improvement of NIHSS score between the group B and the group C(P>0.05).Conclusion:1.“Xingnao Tiaofu” acupuncture treatment of insomnia after stroke is superior to ordinary acupuncture and western medicine in the overall efficacy of the recent.2.“Xingnao Tiaofu” acupuncture treatment of insomnia after stroke was better than Western medicine group in improving the evaluation index.It was better than the normal acupuncture group and western medicine group in the improvement of NIHSS score.3.“Xingnao Tiaofu” group and ordinary acupuncture group for treatment of post-stroke insomnia have similar short-term and long-term curative effects in improving PSQI,HAMD and HAMA evaluation indexes,but “Xingnao Tiaofu” group has the advantages of reducing consumables and save medical expenses which starting from economic benefit,so it is worth further promotion and application.