Study On The Relationship Between Dietary Inflammatory Index And Bone Mass In The Elderly

Objectives(1)To observe whether there are differences in bone mass among different dietary inflammatory index groups(2)To analyze the relationship between bone mass and dietary inflammatory index in the elderly,and to evaluate whether dietary inflammatory index has important clinical significance for the reduction of bone mass in the elderly(3)To analyze the correlation between the characteristics of dietary inflammatory in the elderly,so as to provide early intervention and guidance for the diet of the elderly.MethodsA cross-sectional study was conducted on 400 elderly people aged 65 and over who met the medical examination standard in a community health service center in Beilin District of Xi'an City from May 2018 to October 2018.The general clinical data,bone mineral density(BMD)and dietary inflammatory index(DII)scores of 400 elderly people were counted.Bone mineral density(BMD)was measured by ultrasound.According to the latest consensus of ISCD of International Society of Clinical Bone Density(2018),the diagnosis of osteoporosis was based on the diagnostic criteria of osteoporosis established by the World Health Organization and the Branch of Osteoporosis and Bone Mineral Salt Diseases of Chinese Medical Association:T value>1.0 SD is normal bone mass,-2.5 SD<T value?1.0 SD is osteopenia,and T value?2.5 SD is osteoporosis.400 subjects were divided into three groups according to the above criteria.The dietary data of the elderly were obtained through the food frequency questionnaire,and the dietary components were calculated by the Chinese Food Composition Table(2009).Finally,the individual dietary inflammatory index score was calculated.According to the score of dietary inflammatory index of 400subjects and the score of pro-inflammatory and anti-inflammatory diets,namely,positive dietary inflammatory index score,the pro-inflammatory diet group and negative diet group were identified as anti-inflammatory diet group.Quantile grouping criteria were(Q1?-1.445?-1.444?Q2?0.524?0.525?Q3?1.822?Q4?1.823).ANOVA and variance analysis were used.Kruskal-Wallis H nonparametric test,Chi-square test,Pearson product moment correlation analysis,Spearman rank correlation analysis,linear regression analysis were used to analyze the relationship between dietary inflammatory index and bone mass.Results(1)There was significant difference in bone mass between anti-inflammatory diet group and pro-inflammatory diet group(c~2=84.592,P<0.001),suggesting that the inflammatory characteristics of diet had an effect on bone mineral density in the elderly.(2)The median scores of dietary inflammatory index between osteoporosis and osteopenia and normal bone mass were 1.844,0.470 and-1.215,respectively,with significant difference(c~2=64.243,P<0.001).(3)BMD was negatively correlated with DII score(r=-0.550,P<0.05).After partial correlation analysis of adjusted age and other factors,DII score was negatively correlated with BMD(r=-0.462,P<0.05).The results of linear regression showed that DII score was in line with BMD.(4)The correlation analysis of DII score and other indicators in the pro-inflammatory and anti-inflammatory diet group showed that there was a negative correlation between DII score and diabetes history in the pro-inflammatory diet group,and the correlation coefficient was r=-0.343,P<0.05,while it was positively correlated with smoking history.The correlation coefficient was r=0.317,P<0.05,and had no correlation with other indicators,P>0.05.In the anti-inflammatory diet group,DII score was negatively correlated with BMI and diabetes history,the correlation coefficients were r=-0.201,-0.361,P<0.05,and positively correlated with smoking history.The correlation coefficients were r=0.334,P<0.05,and there was no correlation with other indicators,P>0.05.Conclusion(1)There are significant differences in bone mass among different DII scores in the elderly,which can provide anti-inflammatory diet guidance for the elderly with early bone loss.(2)There is a significant correlation between DII score and bone mineral density in the elderly.The higher the DII score,the lower the bone mineral density and the greater the risk of osteoporosis,which can provide guidance and reference for the clinical prevention of osteoporosis in the elderly.