Study On The Relationship Between Dietary Inflammatory Index And Pre-Diabetes In The Elderly

Objective:(1)To observe whether there were differences between normal blood glucose and prediabetes in the elderly with different dietary inflammatory index scores.(2)To analyze the relationship between prediabetes and dietary inflammatory index.(3)To evaluate whether dietary inflammation index has important clinical significance for patients with pre-diabetes,so as to intervene in the pre-diabetic population from the perspective of dietary structure and delay or prevent their development into diabetes.Methods:A cross-sectional study was conducted on 284 elderly people aged 65 and above who met the inclusion and exclusion criteria during physical examination in Dongguannanjie Community Health Service Center and Hansenzhai Community Health Service Center of Xi ’an from June 2019 to November 2020.The general clinical data and routine biochemical test results of 284 elderly people were analyzed.The diet data of the elderly were obtained through 3-day diet recall.According to the Chinese Food Composition Table(2009 edition),the dietary composition and content of the participants were respectively corresponding,and then the total DII score of participants was calculated.According to the situation of fasting blood glucose,the elderly were divided into normal blood glucose group and prediabetic group,and compared with different DII quartile scores.Chi-square test,Fisher’s exact test,ANOVA,Spearman rank correlation analysis,Logistic regression analysis and other statistical methods were used to analyze the data to explore the relationship between dietary inflammatory index and prediabetes in the elderly.Results:(1)There were statistically significant differences in waist circumference,BMI and triglyceride among different DII quartile groups(P < 0.05).(2)There were statistically significant differences in weight(Kg),BMI,waist circumference(cm)and other related clinical indicators among different groups of the elderly(P < 0.05).(3)There were statistically significant differences between the anti-inflammatory diet group and the pro-inflammatory diet group and the groups with different blood glucose status(c~2=63.588,P < 0.05).(4)There was a positive correlation between dietary inflammation index and prediabetes in the elderly(r=0.603,P < 0.05).After adjusting for weight,waist circumference,BMI,triglyceride and other factors,the partial correlation analysis between dietary inflammation index and prediabetes in the elderly showed a positive correlation(r=0.540,P < 0.05).(5)Binary Logistic regression analysis was conducted with DII score as covariate and prediabetes as dependent variable,and the results showed that there was a statistical significance between DII score and prediabetes(OR=1.462,95%CI :1.228-1.660,P <0.05).After correction for waist circumference,body weight,BMI,triglyceride and other related factors,the results were still statistically significant(OR=1.023,95%CI :0.998-1.126,P < 0.05).Conclusion:(1)In the elderly population,DII was positively correlated with body weight,waist circumference,BMI and triglyceride levels.(2)The prevalence of prediabetes in the elderly with pro-inflammatory diet was higher than that of the elderly with anti-inflammatory diet.(3)There was a significant correlation between dietary inflammation index and prediabetes in the elderly.The higher teh DII score of dietary inflammatory is,the greater possibility of prediabetes in the elderly.DII score was an independent risk factor for prediabetes in the elderly.