Clinical Experience Of Professor Xue Hanrong In Treating Chronic Obstructive Pulmonary Disease

Purpose: To explore Professor Xue Hanrong’s academic ideas,summarize his clinical experience in the treatment of chronic obstructive pulmonary disease(COPD),and explore Professor Xue Hanrong’s medication rules in the treatment of COPD.Methods: The first part summarizes the experience of the tutor in the treatment of COPD by reading ancient literature and the papers and works written by Professor Xue Hanrong,learning from clinical tutors,collecting,sorting out and analyzing the tutor’s medical records.In the second part,we use Traditional Chinese Medicine Inheritance Assistant Platform software to process the collected cases.Through frequency statistics function,prescription law analysis function and new analysis function,based on association rules and entropy clustering,we can get the prescription law of the mentor.Result: The first part is the clinical experience of the tutor in the treatment of COPD.The tutor believes that the etiology and pathogenesis of COPD in TCM are as follows: weakness of Qi and Yang and phlegm and blood stasis in the lungs are internal causes,while exogenous cold is the main cause of acute aggravation;clinical differentiation of symptoms and signs is closely linked to cold and heat,deficiency and excess,Qi and blood,combined with the location of the disease,the disease is dividedinto acute and slow stages;the therapies are based on warming and dredging therapies,with warming Lung Qi,warming lung to eliminate cold,warming lung to eliminate phlegm and retained fluid,warming lung and lowering qi and relieving asthma,warming up Yang Qi,Actively combined with "promote an unimpeded flow,warming-promoting,clearing away heat and dredging,vein relaxing,reinforcing and dredging,relieving exterior syndrome and promoting lung function,purging the bowels and activating the lung,unblock the helm" treatment,applied to the whole course of COPD treatment;in acute phase,the basic treatment is to warm the lung and disperse cold,remove phlegm and remove blood stasis,promote qi and relieve asthma,while in remission period,the basic treatment is to tonifying qi and warming yang to strengthen defensive qi,warm and nourish kidney-yang.The second part is about the medication rules obtained from data mining of medical records.From 142 cases 406 medical records collected,we can get the following results: 1.The frequency of medicines ranked from high to low,and the top 10 were orange peel,Codonopsis pilosula,Rhizoma Pinelliae,Ephedra,Atractylodes macrocephala,almond,Poria cocos,Perilla fructus,ginger and Astragalus membranaceus.2.The most medicines belong to the temperature in the four gases of drugs,the most medicines belong to the spicy flavor in the five flavors of drugs,and the most medicines belong to the lung meridian in the meridian.3.The top 10 pairs of commonly used medicines were Codonopsis pilosula-Atractylodes macrocephala,Ephedra-Almond,Astragalus-Atractylodes macrocephala,orange peel-Codonopsis pilosula,orange peel-Atractylodes macrocephala,Codonopsis pilosula-Bupleurum,Codonopsis pilosula-Astragalus membranaceus,orange peel-Codonopsis pilosula-Atractylodes macrocephala,Codonopsis pilosula-Astragalus membranaceus-Atractylodes macrocephala,orange peel-bupleurum.4.Sixteen core combinations of four commonly used medicines and six corecombinations of five commonly used medicines were obtained.5.9 new prescriptions were obtained.Conclusion:1.The pathogenesis of COPD conforms to the characteristics of "one deficiency,one reality" and "easy deficiency and easy reality",and runs through the whole process.2.The method of treatment pays attention to the academic thought of "treating lung not far from warming lung",and pay attention to the functional characteristics of "keeping lung unobstructed";3.In the treatment,we should pay attention to the urgency of the disease.In the acute stage,the treatment of symptoms is the main method,while in the remission stage,the treatment of root causes is the main method.4.In the use of drugs,the instructor is good at using the drugs pungent in flavor and warm in property,paying attention to promoting and lowering lung qi,reinforcing pectoral qi and promordial qi,reinforcing deficiency of Qi and yang,and not forgetting the reality of purging phlegm and blood stasis.