| Objective: To investigate the prevalence of chronic kidney disease(CKD)and related risk factors in hearing impaired children in Hunan province.Methods: Using cross-sectional study,take the method of multistage cluster sampling,Hunan province were selected in the two cities or autonomous prefectures,respectively to extract a hearing impairment,150 children were selected from the hearing impairment institutions,and a total of 1,500 children were selected as research samples.On-site questionnaire survey,physical examination,laboratory examination.Results: 1.In this survey,1,459 children aged 2-14 years old have complete data,including 818 boys and 641 girls.There were statistically significant differences in height and weight between men and women(P<0.05),and significant differences in serum creatinine(Scr),glomerular filtration rate(eGFR),and blood uric acid(BUA)(P < 0.01).2.The total number of patients with CKD in the total population was43,with the prevalence rate of 2.95%.The prevalence was 2.93% in boys and 2.96% in girls,and the difference between males and females was not statistically significant(P > 0.05).The prevalence of CKD in group A(<7years old)was 5.79%,and that in group B(7 years old)was 0.94%.The prevalence of CKD in group A was significantly higher than that in group B,and the difference was statistically significant(P<0.01).The prevalence of CKD was 0.45%,0.94%,2.29% and 5.69% in children with mild to extremely severe degree of hearing impairment,respectively.The higher the degree of hearing impairment was,the higher the prevalence of CKD was,and the difference was statistically significant(P<0.01).The prevalence of CKD was 0%,0.28%,9.7%,19.57% and28.57%,respectively,for children with nutritional classification of overweight,normal,mild,moderate and severe malnutrition.The higher the degree of nutritional impairment,the higher the prevalence of CKD was,and the difference was statistically significant(P< 0.01).Among the43 children diagnosed with CKD this time,13 children were previously diagnosed with CKD,so the awareness rate of CKD population was30.23%,and 5 children had a family history of genetic disease,which was about 11.63%.Always diagnosed with chronic glomerular diseases in children with nine people,about 20.93%,form and the B ultra inspection found Congenital kidney and urinary tract malformation(Congenital anomalies of the kidney and urinary tract,CAKUT)children in 14 cases,about 32.56%,other etiology is unknown.3.The prevalence rates of hypertension,diabetes,abnormal lipid metabolism and hyperuricemia were 2.26%,0.21%,1.85% and 1.85%,respectively.The differences in the prevalence of hypertension,diabetes,abnormal lipid metabolism and hyperuricemia in children with different degrees of hearing impairment were statistically significant(P<0.01).Children with chronic kidney disease(CKD),chronic kidney disease(CKD)children high blood pressure,diabetes,abnormal lipid metabolism,high uric acid hematic disease prevalence(55.81%,0.64%),respectively(4.65%,0.07%),(30.23%,0.99%),(18.6%,1.34%),chronic kidney disease(CKD)with the children's high blood pressure,diabetes,chronic kidney disease(CKD),lipid metabolic disorder and high uric acidhematic disease prevalence differences significant statistical significance(P< 0.01).4.Multivariate logistic regression analysis showed that hypertension,nutritional disorder and hearing impairment were independent risk factors for CKD.Conclusions: 1.The prevalence of CKD in hearing impaired children in hunan province was 2.95%,higher than that in normal children nationwide,and most of them were in the early stage and early school age of CKD.Chronic glomerular disease(20.93%)and CAKUT(32.56%)were the major causes of the disease.2.Hypertension,nutritional impairment and hearing impairment are independent risk factors for CKD in children aged 2-14 years in Hunan province. |
PDF Full Text Request