| Objective: To explore the curative effect of Jiawei Liujunzi Decoction combined with pestle needle in the treatment of functional dyspepsia of spleen deficiency and qi stagnation syndrome,and to compare the difference in curative effect between pestle needle and Jiawei Liujunzi Decoction.Methods: According to Rome IV diagnostic criteria and TCM syndromes diagnostic criteria,99 patients with functional dyspepsia of spleen deficiency and qi stagnation syndrome from March 2018 to January 2019 were collected and randomly divided into three groups(group A,group B and group C)in chronogical the order of visits.Group A was treated with Modified Liujunzi Decoction combined with pestle needle,and one dose of Modified Liujunzi Decoction per day.Water decoction,three warm clothes,150 ml each time,4 weeks for a course of treatment,one course after the end of treatment.The treatement of pestle needle,complementary method is used in all cases for 30 minutes each time,once every other day,and 15 consecutive times.Group B was treated with pestle needle only,and the treatment method and course were the same as that of group A.Group C was treated with modified Liujunzi Decoction only,and the treatment method and course were the same as that of group A with traditional Chinese medicine decoction.To evaluate the efficacy and safety of Jiawei Liujunzi Decoction combined with pestle needle therapy and to compare their differences in curative effect by comparing the scores of TCM syndromes,single symptom,anxiety and gastric emptying function before and after treatment.SPSS23.0was used to analyze the different classification data and draw conclusions.Result:(1)After treatment,the total effective rates of the three groups were 96.67%,86.67% and 86.67%,respectively.There was no significant difference between groups,and there was no statistical significance(P>0.05).(2)The total effective rates of the three groups in follow-up visit were 93.30%,80.00% and 86.67%,respectively.There was no significant difference among the three groups and there was no statistical significance(P>0.05).(3)Compared with TCM syndromes,there was significant difference before and after treatment in each group(P<0.05).There was significant difference among the three groups and there was statistical significance after treatment(P>0.05);and follow-up in groups,there was significant difference between group A and group B and group C(P<0.01,P<0.05),but there was no significant significance between group B and group C neigher after treatment nor follow-up(P>0.05).(4)Compared with the single symptoms before and after treatment,the three groups had different degrees of relief after treatment,with significant difference(P<0.05).The improvement of fatigue and loose stool in group A was better than that in the other two groups(P<0.01,P<0.05),and the other symptoms had no significant difference(P>0.05).(5)One month later,compared with single symptoms,group A was superior to group B in diet deficiency,fatigue,fatigue,yellowish complexion and loose stool(P<0.05,P<0.01),In the long-term efficacy of fatigue,pale complexion and loose stool,group C was superior to group C(P<0.05),but there was no significant difference between group B and group C(P>0.05).(6)Anxiety scores were significantly lower in the three groups after treatment and follow-up than before treatment,with statistical significance(P<0.05).Compared in groups after treatment and follow-up,there was statistical significance in group A(P<0.05),while there was no significant difference between group B and group C(P>0.05).(7)Comparing the gastric emptying function,the antral contraction rate and gastric emptying rate of the three groups after treatment were significantly increased compared with those before treatment,and there were statistical differences in the three groups(P<0.05);But there was no significant difference between the groups(P>0.05).(8)Safety observation showed that there were no obvious abnormalities in laboratory examination and electrocardiogram in the three groups,and no obviousadverse reactions occurred during the whole test process.Conclusion: Jiawei Liujunzi Decoction combined with pestle needle has good and stable clinical efficacy in treating functional dyspepsia of spleen deficiency and Qi stagnation,and the effect of purely using pestle needle therapy is comparable to that of simply using modified Liujunzi decoction.The three treatment methods have no obvious adverse reactions,safe and effective,high acceptance of patients,and can be promoted in clinical practice. |
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