Clinical Efficacy Of Paravertebral Nerve Block With Interferon ?--2b In The Treatment Of Metastatic Spinal Tumors

Objective:To study the clinical effect of interferon ?--2b on paravertebral nerve block in patients with metastatic spinal tumors.Methods:Sixty cancer patients with spinal metastasis were enrolled in our hospital from January 2017 to March 2018,of which patients divided into interferon ?--2b group(group A)and control group(group B)randomly.The only difference between group A and B was whether to use the interferon ?--2b or not.The clinical efficacy,visual analogue scale(VAS)of pain,number of pain episodes,the quality of sleep,daily consumption of morphine and adverse reactions were recorded and compared between the two groups.Results:The VAS score,each index score and total score of PSQI,the daily consumption of morphine,the number of pain episodes,and the adverse reaction rate were lower in group A than in group B(P<0.05),the remission rate of group A was higher than that of group B(P<0.05).No serious adverse reactions occurred in any of the groups.Conclusion:Interferon ?--2b used in paravertebral nerve block for patients with metastatic spinal tumors can improve pain symptoms and sleep quality,reduce the dose of opioids and related adverse reactions.