The Investigation Of Coagulase Negative Staphylococcus In Nasal Vestibule From The Infants Of Neonatal Ward

Objective: We aimed to investigate the association factors of coagulase negative Staphylococcus(CoNS)colonization in nasal vestibule in the infants of neonatal ward,and the predictive value of the CoNS colonization to the clinical outcomes.Methods: Oct.2013 to Sept.2014,there were 23 CoNS positive cases,and 75 cultrue negative cases matched with which were settled.The general conditions,perinatal conditions,Apgar score,laboratory examinations,treatments and outcomes were analyzed.The analysis was conducted with SPSS 19.0,and P<0.05 represent significant difference.Results:1.There were no significant differences in birth weight,gestational age or gender.But the day of age in observation group was higher than in the control group,P<0.001.2.The incidence of maternal antenatal complications,including PROM,meconium stained amniotic fluid(MSAF),GDM,PHD,thyroidism disorders,placental abnormalities and HELLP syndrome,was higher in the control group,P<0.0001.There into,the incidences of PROM and MSAF were higher in control group,P was 0.006 and 0.024 respectively.While there were no significant differences in the incidences of the other disorders between the two groups.3.As for the laboratory measurements,there were no differences in the complete blood count,serum biochemical test,blood and urine culture,procalcitonin.CRP was higher in control group,P was 0.009.4.There were no significant differences in the etiologies,including hyperbilirubinemia,NRDS,respiratory system disease,cardiovascular disease or digestive system disease.5.There were no differences in the rates of antibiotic treatment or intubation rate between the two groups either,as well as the length of hospital stay.Conclusion:1.The incidence of CoNS colonization in neonatal ward is associated with days of age.2.There is no significant difference between the clinical outcomes and CoNS colonization.3.The coagulase negative staphylococci in nasal vestibule collected on admission from the infants who were born in our obstetric wards had no significant prediction value for infection.