| Objective: To observe the clinical efficacy and safety of Qianjinweijing Decoction and Shengmai Powder on postoperative rehabilitation of non-small cell lung cancer patients with phlegm and blood stasis and qi and yin deficiency.Methods: According to the inclusion and exclusion criteria of this study,61 patients in the Department of Oncology and Cardiothoracic Surgery of the Affiliated Hospital of Chengdu University of Traditional Chinese Medicine from February 2017 to March 2019.30 patients in the treatment group and 31 patients in the control group.The control group: pulmonary functional exercise.On the basis of the control group,the treatment group took Qianjinweijing Decoction and Shengmai Powder.Clinical efficacy and safety were evaluated from KPS scores,Cough symptom score,body weight,TCM syndrome,leukocyte and adverse events.Results: According to the data analysis: 1.There was significant difference in KPS scores between the treatment group and the control group after treatment(P<0.05).2.There was a statistically significant difference in body weight between the treatment group and the control group after treatment(P <0.05).3.There was a statistically significant difference in the reduction of cough symptom scores(daytime scores,nighttime scores,and total scores)between the treatment group and the control group(P <0.05).4.Compared the TCM syndrome scores between the treatment group and the control group,the treatment group was superior to the control group(P <0.05),Especially in cough,sputum,shortness of breath,chest pain,fatigue,dry mouth,dryness,spontaneous sweating and sweating.5.The changes of white blood cells in the treatment group and the control group were decreased,The effect of the treatment group was better than that of the control group(P<0.05).There were statistical differences.6.Safety indicators showed that only a few patients had symptoms ofdiarrhea,indicated the good safety.Conclusion: Qianjinweijing Decoction and Shengmai Powder can improve postoperative KPS score,reduce Cough symptom score and TCM syndrome,increase body weight and reduce white blood cell level,have good postoperative rehabilitation for patients with non-small cell lung cancer with phlegm and blood stasis and qi and yin deficiency. |