| Objective:This thesis aims to compare the clinical efficacy of ultrasound-guided microwave ablation and traditional surgery for benign thyroid nodules,and to confirm the therapeutic effect and safety of ultrasound-guided microwave ablation for benign thyroid nodules.Methods:110 patients with benign thyroid nodules treated in our hospital from January 2017 to December 2018 were enrolled in the study.They were divided into microwave ablation group(n=60)and open surgery group(n=50).The treatment status of the two groups(including intraoperative blood loss,operation time,postoperative hospital stay,hospitalization cost,postoperative surgical wound length,and wound cosmetic score)were recorded and compared.The pain score(VAS)of the patients was compared in the two groups were compared 12 h after surgery and 24 h after surgery.Patients were followed up for 12 months after surgery.The changes of thyroid nodule volume,and record the volume reduction rate of thyroid nodulesat 1 month postoperatively,3 months postoperatively,6 months postoperatively,and 12 months postoperativel were observed.The thyroid hormone levels were measured at 6 months after surgery in both groups.The thyroid hormone levels in the microwave ablation group and the open surgery group were compared before and 6 months after surgery(including: TSH,FT3,TT4).Results:Comparison of treatment status between the two groups: The amount of intraoperative blood loss in the microwave ablation group was significantly lower than that in the open surgery group(P <0.05),and the operation time in the microwave ablation group was significantly shorter than that in the open surgery group(P <0.05).The postoperative hospital stay in the microwave ablation group was significantly less than that in the open surgery group(P <0.05).There was no significant difference in hospitalization costs between the microwave ablation group and the open surgery group(P >0.05).The length of postoperative wounds in the microwave ablation group was significantly shorter than that in the open surgery group(P <0.05).The cosmetic score of the patients in the microwave ablation group was significantly higher than that in the open surgery group(P <0.05).The VAS scores of the patients in the microwave ablation group were significantly lower than those in the open surgery group at 12 h and 24 h after surgery(P <0.05).2.Comparison of postoperative complications in the two groups: the incidence of postoperative complications in the microwave ablation group was 5.00%(3/60),and the incidence of postoperative complications in the open surgery group was 18.00%(9/50),the difference in postoperative complication rates between the two groups was statistically significant(P < 0.05).3.Comparison of thyroxine levels between the two groups: The TSH level of the open surgery group was significantly higher than that of the microwave ablation group at 6 months after operation(P <0.05).The TSH level of the open surgery group was significant at 6 months after operation.Higher than the preoperative TSH level(P <0.05).The FT3 level of the open surgery group was significantly lower than that of the microwave ablation group at 6 months after operation(P <0.05).The FT3 level of the open surgery group at 6 months after operation was significantly lower than that of the preoperative FT3 level(P <0.05).The level of TT4 in the open surgery group was significantly lower than that in the microwave ablation group at 6 months after operation(P <0.05).The TT4 level in the open surgery group was significantly lower than that in the preoperative TT4 level at 6 months(P <0.05)..4.Changes in postoperative thyroid nodules in the microwave ablation group: the residual rate of nodules at the 6th month after microwave ablation was 80.00%,and the nodules at the 12 th month after microwave ablation The residual rate was 51.43%,and the average volume of nodules was significantly reduced at 12 months after microwave ablation.The difference was statistically significant compared with preoperative(0.42±0.14 cm VS 12 months postoperatively 2.78±0.74 cm preoperative)<0.05),the volume average reduction ratio of the nodules was 85.61%.Conclusion:Ultrasound-guided microwave ablation can significantly reduce the volume of thyroid nodules in patients,with a high average volume reduction rate,and even some patients can achieve the disappearance of thyroid nodules,is an effective method for the treatment of benign thyroid nodules.Compared with traditional open surgery,ultrasound-guided microwave ablation has the advantages of less complications,shorter hospital stay,shorter operation time,less intraoperative blood loss,better wound cosmetic effect,and less impact on patients' thyroid function.Ultrasound-guided microwave ablation is the treatment of choice for benign thyroid nodules. |
PDF Full Text Request