Analysis Of The TCM Syndrome Types And The Relative Factors Of Diabetic Retinopathy

objectiveThrough the retrospective study on the case data of type 2 diabetic retinopathy(DR),the risk factors and the distribution of common TCM syndromes of DR were analyzed to provide reference for clinical diagnosis and treatment.Methods120 DR patients and 60 non-DR patients in our hospital were selected to record the general situation of all patients,the information of four diagnoses of traditional Chinese medicine,clinical and biochemical indicators.At the same time,the designed questionnaire of TCM syndromes was used to collect the data of four diagnoses,accumulate integrals,use data mining method,cluster analysis,combined with clinical summary of the main syndromes,and logistic regression analysis method was used.The clinical and biochemical indicators were summarized and analyzed to explore the relationship between these indicators and DR.Results(1)According to cluster analysis of TCM syndromes of 120 DR patients,120 DR patients can be classified into 6 types.According to the frequency of occurrence,they are Qi deficiency and blood stasis,Qi-Yin deficiency,liver and kidney deficiency,Yin deficiency and blood stasis,blood stasis and phlegm coagulation,spleen and kidney deficiency.(2)Compared with NDR group,age,course of disease,high density lipoprotein cholesterol(HDL-C),total triglyceride(TG),uric acid(UA),24-hour urinary microalbumin(24-hour UMA),urinary microalbumin/creatinine ratio,P<0.05,the difference was statistically significant;at the same time,regression analysis of the above indicators showed that the course of disease,age,UA abnormality,24-hour UMA,the abnormalities of UACR and TG are the related risk factors for DR,and the increase of HDL-C may be the protective factor.ConclusionsThe common syndromes types of DR patients are Qi deficiency and blood stasis,Qi-Yin deficiency,liver and kidney deficiency,Yin deficiency and blood stasis,blood stasis and phlegm coagulation,spleen and kidney deficiency.The course of disease,age,TG abnormality,UA abnormality,24-hour UMA abnormality,UACR abnormality are the related risk factors of DR.The increase of HDL-C may be the protective factor of DR.