| Objective: To observe the clinical effect of Shuluo-Tongmai therapy on stable angina pectoris of coronary heart disease(Mailuo Stasis Syndrome),and to provide effective clinical ideas and practical experience for the prevention and treatment of stable angina pectoris of coronary heart disease with integrated traditional Chinese and Western medicine.Methods: Sixty-six patients with stable angina pectoris and Mailuo Stasis Syndrome were selected from the second outpatient department of Cardiology of Shanxi Hospital of Traditional Chinese Medicine.The patients were divided into treatment group and control group by statistical random number table method.Sixty patients were finally tested.There were 30 patients in each group.After statistical analysis,the basic data of treatment group and control group had no significant difference.Two groups of patients were given smoking cessation,alcohol and other lifestyle improvement education and conventional western medicine prevention and treatment of coronary heart disease.On this basis,the treatment group was added with Bawei Tongluo Granule developed according to the method of dredging collaterals and dredging veins.The control group was given Bawei Tongluo Simulated Granule for12 weeks.Angina score and its curative effect,TCM symptom score and its curative effect,treadmill exercise test transport were observed and compared between the two groups.The duration of exercise,maximum heart rate,metabolic equivalent(METs),maximum decrease of ST segment(m V),Duke score,evaluation of Seattle Angina Scale,changes of blood lipid before and after treatment and safety quantification index were used to determine the clinical efficacy and safety of Shuluo Tongmai method.Result:(1)Clinical scores and curative effect of angina pectoris: There were significant differences between the treatment group and the control group at 12 weeks before and after treatment(P<0.01);the treatment group was significantly better than the control group(P<0.01);There was a statistically significant difference between the twogroups(P<0.05).It can be considered that the clinical symptoms of angina pectoris in the treatment group were better than those in the control group.(2)TCM syndrome scores and curative effect: After the treatment,the total scores of TCM syndromes,main symptoms and secondary syndrome scores of the two groups before and after treatment were statistically significant(P<0.05,P<0.01).There was significant difference between the groups(P<0.01).The comparison between the treatment group and the control group was better than that of the control group(P<0.01).The results were statistically significant.The treatment group improved the symptoms of TCM syndrome and the medical effect was better than the control group.(3)Tread exercise test: The duration of exercise,METs,maximum heart rate,maximum ST depression(mv),and Duke score were significantly statistically significant(P<0.01).Compared with the control group,the duration of exercise,METs,maximum heart rate,maximum ST depression(mv),Duke score and other indicators were statistically significant(P<0.05,P<0.01).Group improvement was more pronounced than the control group.(4)Seattle angina pectoral scale: There was no significant difference between the stable state of angina after treatment and the treatment before treatment(P>0.05).The two groups of patients were compared with the degree of physical activity limitation,angina pectoris,angina pectoris,treatment.There was a statistically significant difference in the degree of satisfaction and awareness of the disease(P<0.05).The Seattle Angina Scale Evaluation Treatment Group was superior to the control group.(5)Four items of blood lipids: After treatment,TC,TG,LDL-C levels decreased and HDL-C levels increased after treatment(P < 0.05);TC,TG,LDL-C,HDL-C after treatment in the treatment group The level of HDL-C was lower than that of the control group(P<0.05).(6)There was no significant difference in blood,urine,stool routine,ALT,AST and renal function before and after treatment(P > 0.05);fasting blood glucose increased in2 patients in the treatment group and 1 patient in the control group during the experiment,and the overall blood sugar had no significant significance by statistical analysis(P > 0.05);no adverse reaction symptoms were complained in 2 groups.Conclusion: Shuluo-Tongmai Method can significantly improve the symptoms of angina pectoris in patients with stable angina pectoris.It can reduce the occurrence of myocardial ischemic events;It can significantly improve the clinical symptoms of TCM patients with stable angina pectoris,significantly reduce TCM syndrome scores;It can improve myocardial oxygen supply capacity,increase myocardial cell tolerance,enhance coronary blood supply capacity,effective Improving the amount of exercise and improving the prognosis can reduce the patient's activity restriction,reduce the incidence of angina pectoris,improve the patient's satisfaction with the treatment,increase the patient's understanding of the disease;It can improve the patient's blood lipid level and reduce TC,TG,LDL-C to a certain extent,Increase HDL-C levels. |
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