| Objective:To assess the efficacy and safety of plastic wrap for prevention of hypothermia in newborn Infants.Medthods:We searched databases including Cochrane Library,Pubmed,Scopus,Cinahl,CBM,CNKI,VIP,and Wanfang.We included all randomized controlled trials which investigated the efficacy and safety of plastic wrap on prevention of hypothermia in newborn infants.Studies were selected according to inclusion and exclusion criteria,extracting data and assessing quality.Then,RevMan 5.2 software was used to analyze the data.Results:Sixteen randomized controlled trials which included 2836 participants were included.The results of meta-analysis showed that premature Infants in plastic wrap group hypothermia and moderate hypothermia on admission to the NICU[RR=0.71,95%CI(0.64,0.79),p<0.00001;RR=0.53,95%CI(0.39,0.73),p=0.00001],core body temperature on admission to the NICU or up to one hours[MD=0.60,95%CI(0.47,0.72),p<0.00001;MD=0.48,95%CI(0.33,0.63),p<0.00001]and core body temperature on admission to the NICU for infants at<28 weeks’ gestation and at≥ 28 weeks’ gestation[MD=1.22,95%CI(0.88,1.56),p<0.00001;MD=0.4,95%CI(0.26,0.55),p<0.00001]compared with routine care group had significantly statistical difference;However there was no significant difference in risk of mild hypothermia on admission to the NICU[RR=1.07,95%CI(0.27,4.22),p=0.92],incidence of IVH(grades Ⅲ or Ⅳ)[RR=0.92,95%CI(0.65,1.32),p=0.66]and death during hospital stay[RR=0.75,95%CI(0.53,1.08),p=0.12].Risk of hyperthermia on admission to the NICU was increased in infants in the wrapped group[RR=4.09,95%CI(2.12,7.88),p<0.0001].Conclusion:Evidence of moderate quality shows that use of plastic wraps compared with routine care led to higher temperatures on admission to NICUs with less hypothermia,caution must be taken to avoid iatrogenic hyperthermia,along with lack of power to detect effects on IVH(grades Ⅲor Ⅳ)and mortality across comparison groups.lack of power to detect effects on the efficacy and safety of plastic wrap in full-term infants. |
