Study On Relationship Between Estrogen Level, Serum Calcium And Phosphorus Metabolism Concentration With Benign Paroxysmal Positional Vertigo

Objective:To investigate the clinical relationship between estrogen level,serum calcium and serum inorganic phosphorus concentration and benign paroxysmal positional vertigo(BPPV).Methods:A total of 84 patients with idiopathic BPPV were enrolled in the experimental group,including 32 non-menopausal women,24 menopausal women,and 28 males.83 healthy people without vertigo and vestibular disease were selected as the control group.There were 32 non-menopausal women,24 menopausal women and 27 males.The levels of estradiol,serum calcium and serum inorganic phosphorus were measured in all participants.The difference of estrogen level,serum calcium and serum inorganic phosphorus concentration between the experimental group and the control group was analyzed by t test.Results:1.The total number,age distribution and gender composition of the experimental group and the control group were basically the same,and the age difference was not statistically significant(P value was 0.71).2.The overall estrogen level in the experimental group was lower than that in the control group(P<0.001),the difference is statistically significant,Among them,the female group's estrogen level,menopausal female estrogen level and male estrogen level in the experimental group were lower than the control group(P value was less than 0.001),the difference was statistically significant.3.the experimental group serum calcium and serum inorganic phosphorus concentration and There was no significant difference in the control group(P values were 0.55 and 0.11,respectively).Conclusions:1.The decrease of estrogen level may be a risk factor for idiopathic BPPV.2.The relationship between serum calcium and serum inorganic phosphorus concentration and BPPV needs further study.