Correlation Between Sleep Disorders And Cardiac Function After Percutaneous Coronary Intervention Following Acute Myocardial Infarction

Objective:The cardiac function of patients with acute myocardial infarction(AMI)after percutaneous coronary intervention(PCI)is related to many factors.Sleep disorders are closely related to cardiovascular diseases,so sleep disorders and AMI The correlation of cardiac function after PCI is worthy to discussion.Methods:112 patients who underwent emergency PCI for acute ST-segment elevation myocardial infarction in the Department of Cardiology,Jiujiang University Affiliated Hospital from December 1,2015 to November 30,2018.All patients were hospitalized for the first time.There was no history of coronary heart disease,and there was no evidences of myocardial ischemia in ECG and cardiac ultrasound.This study used a retrospective survey to collect baseline data and clinical data from patients,and used the Pittsburgh sleep quality index(PSQI)to score the patient's sleep on 1 month before hospitalization.Patients were divided into sleep disorder group and sleep normal group according to the score.Collect general patient information,admission diagnosis,and myocardial infarction.Data analysis was performed using SPSS 19.0 software.Results:1.Comparison of general data showed that the sleep disorder group was older than the normal sleep group(64.72 ± 7.36 vs 59.03 ± 6.84),and the Body mass index(BMI)was higher(23.7 ± 2.78 vs 21.0 ± 2.86).Patients with hyperlipidemia or hypertension were more likely.The difference was statistically significant(P<0.05).However,there were no significant differences in gender,smoking,diabetes,and revasculariz-ation time between the two groups(P>0.05).2.The results of myocardial infarction showed that the results showed that 32 patients(66.67%)with multivessel disease in the sleep disorder group,significantly more than 30 patients(46.88%)in the normal sleep group,the difference was statistically significant(P<0.05).There was no significant difference in myocardial infarction between the sleep disorder group and the normal sleep group(P>0.05).3.The comparison of cardiac color Doppler parameters after PCI showed that the left ventricular ejection fraction(LVEF)in the sleep disorder group was lower than that in the normal sleep group(48.04 ± 4.52 vs 50.83 ± 5.11),and the difference was statistically significant(P<0.05).In addition,left ventricular end-diastolic dimension(LVEDD)in the sleep disorder group was higher than that in the normal sleep group(54.72 ± 5.56 vs 52.93 ± 5.08),and left ventricular end-systolic dimension(LVESD)in the sleep disorder group was also higher than that in the normal sleep group(42.43 ± 4.61 vs 39.65 ± 4.73).All were statistically significant(P < 0.05).4.Univariate analysis of changes in cardiac color Doppler parameters after PCI showed age,female,hyperlipidemia,diabetes,hypertension,revascularization time,multivessel disease,left anterior descending vascular occlusion,anterior myocardial infarction,and Sleep disturbance may be a risk factor for cardiac function decline after PCI in acute myocardial infarction,and the difference was statistically significant(P<0.05).Smoking and BMI did not show risk factors for cardiac decline,and the difference was not statistically significant(P>0.05).To rule out the effects of age,hypertension,hyperlipidemia,and diabetes on sleep function and cardiac function after PCI,we adjusted for age,hypertension,hyperlipidemia,and diabetes by multivariate logistic regression analysis.The results showed that the difference was still statistically significant(P<0.05).After further adjustment of the number of diseased vessels,infarct-related blood vessels and myocardial infarction,the difference was still statistically significant(P<0.05),suggesting that sleep disturbance is a risk factor for cardiac function decline after PCI in acute myocardial infarction.Conclusious:Sleep disorder is an independent risk factor for cardiac dysfunction after PCI in patients with acute myocardial infarction.In addition,cardiac function in patients with acute myocardial infarction after PCI is also affected by a variety of factors,including age,gender,hyperlipidemia,diabetes,hypertension,revascularization time,multivessel disease,target vessel,and myocardial infarction site.