| Objective:The theoretical foundation of thoughts of treatment of insomnia based on Heart and Gallbladder Qi deficiency were discussed.Through this clinical trials,the clinical efficacy of the evaluation was observed and evaluated.The academic theory of treating insomnia from the heart and gallbladder Qi deficiency theory were enriched,the thinking and method for the clinical treatment of insomnia from heart and gallbladder Qi deficiency theory were also broadened.Methods:In this paper,based on the systematic review and analysis of the literature on the treatment of insomnia of the ancient and modern doctors,the origin,etiology and pathogenesis,the main points of syndrome differentiation,treatment methods,selection of the drug,complex treatment and so on of heart and gallbladder Qi deficiency insomnia were selected to carry out in-depth discussion and systematic summary.Using simple randomization method,68 insomnia patients who met the inclusion criteria were divided into treatment group and control group,34 cases each.The control group was treated with zolpidem tartrate,the treatment group was treated with Anshen Dingzhi pills plus subtraction prescription on the basis of the control group,and the two groups were treatment for 4 weeks respectively,sleep time,Pittsburgh Sleep Index Scale(PSQI)score and insomnia heart and gallbladder Qi deficiency Syndrome Scale score were observed before and after treatment.Results:Before treatment,the baseline data of age,sex,personality,occupation,course of disease,and severity of the two groups had no significant difference,and were comparable.The research and observation were scientific and credible.Comparison of insomnia curative effect:?Comprehensive curative effect:12 cases(35.3%),5 cases(14.7%),14 cases(41.2%)were effective and 3 cases(11.8%)were ineffective in the treatment group;6 cases(17.6%)were cured in the control group,3 cases(11.8%)were significantly effective,17 cases(50.0%)were effective,8 cases(26.4%)were ineffective,the total effective rate was 76.4%,and the marked effective rate was 26.4%.By comparison,the comprehensive curative effect of the treatment group was better than that of the control group.(P<0.05).?Fall asleep time:After treatment,the sleeping time of the two groups was significantly shortened(P<0.01),and the sleeping time of the treatment group was significantly shorter than that of the control group(P<0.01).?Sleeping time:After treatment,the sleep time of both groups increased significantly(P<0.01),and the sleep time of treatment group increased more significantly than that of control group(P<0.05).It shows that the clinical effect of insomnia based on heart and gallbladder Qi deficiency can be significantly improved by adding Anshen Dingzhi pills.PSQI score comparison:? Total score comparison:After treatment,the total score of the two groups decreased significantly(P<0.01),and the total score of the treatment group decreased more significantly(P<0.01).?Comparison of PSQI scores:After treatment,the scores of the two groups were significantly lower than those before treatment(P<0.05).After treatment,the scores of sleep quality,fall asleep time,sleep efficiency,da)ytime dysfunction(P<0.01),sleep disorder(P<0.05)were improved more significantly in the treatment group,and there was no significant difference in sleep time and hypnotic drugs(P>0.05).The results showed that the PSQI score could be reduced and the sleep quality could be improved by adding Anshen Dingzhi Pills.After treatment,the sleep time of both groups increased significantly(P<0.05),and the treatment group xwas obvious improved compared with that in the control group(P<0.05).Comparison of therapeutic effects of insomnia with Heart and Gallbladder Qi Deficiency syndrome:?Comparisons of syndrome curative effect:In the treatment group,15(44.1%)were markedly effective,19(55.9%)were effective,the total effective rate was 100%,the marked effective rate was 44.1%;in the control group,26(76.4%)were effective,8(23.6%)were ineffective,and the effective rate was 76.4%.After examination,the curative effect of TCM syndromes in the treatment group was significantly better than that in the control group((P<0.05).?Syndrome score:After treatment,the scores of both groups decreased significantly(P<0.01),and the decrease of the treatment group was more obvious(P<0.01).?Comparisons of symptoms:After treatment,the scores of symptoms in both groups were significantly lower than those before treatment,in which the pulse of the treatment group was smaller than P<0.05,and the other P<0.01;in the control group,the complexion was not brilliant,the tongue was fat,and the pulse was smaller than P>0.05,the spontaneous sweating P<0.05,and the other P<0.01.After treatment,the scores of symptoms in the treatment group were lower than those in the control group.There were significant differences in timidity and fright,palpitation and restlessness,shortness of breath and laziness,and spontaneous sweating(all P<0.01),fatigue and fatigue,no significant difference in complexion(all P<0.05),and no significant difference between the two groups(P>0.05).It is suggested that the addition and subtraction of Anshen Dingzhi Pill can significantly improve the symptoms of insomnia with heart-gallbladder-qi deficiency syndrome,and the curative effect of TCM syndrome is better than that of Western medicine alone.Conclusion:On the basis of routine hypnotic drug therapy,Anshen Dingzhi Pills can significantly shorten the sleeping time,prolong the sleeping time,reduce the PSQI score and improve the quality of sleep.The comprehensive effect is better than that of simple treatment.It can also significantly improve the main symptoms of insomnia,such as timidity,fright,palpitation,fatigue and fatigue,shortness of breath and lazy speech,and poor complexion.It shows that Anshen Dingzhi Pills can effectively improve the symptoms of insomnia with Heart and Gallbladder Qi Deficiency syndrome.At the same time,the use of Anshen Dingzhi pills did not see adverse reactions,good safety,worthy of clinical application. |
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