Clinical Analysis Of Relevant Factors Of Epilepsy Secondary To Cerebral Infarction

Cerebral infarction has high morbidity,disability,mortality and recurrence rate.Epilepsy secondary to cerebral infarction is a common complication to cerebral infarction,It can affect the patient's recovery;and even promotes death.With the aging of the population,The incidence of cerebral infarction and epilepsy secondary to cerebral infarction increased year by year.Therefore,it is imperative to find risk factors of epilepsy secondary to cerebral infarction,and to prevent and treat it.Research purposes:By collecting detailed medical history and clinical data of patients with epilepsy secondary to cerebral infarction and those without secondary cerebral infarction,the related factors of epilepsy secondary to cerebral infarction were analyzed.Research method:1.Research object:From January 2018 to January 2019,all the patients with neurological medicine of the Sino-Japanese Friendship Hospital of Jilin University who were diagnosed with epilepsy secondary to cerebral infarction for the first time were 59 cases.This group of patients meets the following criteria:Inclusion criteria:(1)Diagnosis of acute cerebral infarction by head magnetic resonance examination,or a clear history of only one cerebral infarction after the diagnosis;(2)The admission for the first time seizures;(3)Excluding seizures caused by encephalitis,hemorrhagic stroke,intracranial space and other causes;(4)Improve the EEG examination during hospitalization.Exclusion criteria:(1)A history of previous cerebral infarctions,or an unclear time history;(2)Have had seizures or similar seizures before being diagnosed with cerebral infarction;(3)The brain has other diseases such as encephalitis,hemorrhagic stroke,head trauma,occupying,intracranial parasites,etc.;(4)There may be other causes of seizures,such as recent oral epileptics,metabolic diseases,etc.;(5)familial genetic history of epilepsy.And randomly selected earlier diagnosis of cerebral infarction 60 patients with epilepsy not for the control group,conducted a case-control to study.2.Case grouping:(1)According to whether there is seizure after cerebral infarction,it is divided into epilepsy(EP)group and non-epileptic(NEP)group.(2)The EP group was divided into early-onset seizure(ES)group and delayed-type seizure(LS)group according to the seizure time after cerebral infarction.(3)The EP group was divided into focal seizures,focal secondary general seizures,and general seizures according to the type of seizures.3.Case collection content:Gender,age,NIHSS score,type of cerebral infarction,Infarction site,infarct size,seizure time after infarction,type of seizure,EEG,magnetic resonance data of the head,etc.4.Statistical methods:Statistical analysis method:All data were analyzed by SPSS25.0 statistical software.The count data were analyzed by chi-square test,and the measurement data were analyzed by independent sample t test.P<0.05 was considered to be statistically significant.Research result:Univariate analysis of factors of the EP group and NEP groups:There were significant differences in the history of diabetes,cerebral infarction area and cerebral infarction between the two groups(P<0.05).Large areas of cerebral infarction,located in the cortical infarct is more likely to secondary epilepsy.According to the seizure time after cerebral infarction,the EP group(59 cases)was divided into ES group(13 cases)and LS group(46 cases).The types of cerebral infarction,cerebral infarction area,cerebral infarction and seizure time were analyzed.RESULTS:There was a statistically significant difference in the type of cerebral infarction and the area of cerebral infarction and seizure time(P<0.05).According to the type of seizure,the EP group(59 cases)was divided into the focal seizure group(10 cases),the focal secondary comprehensive seizure group(14 cases),and the comprehensive seizure group(35 cases).There was no significant difference in the analysis of cerebral infarction area,cerebral infarction location,seizure time and seizure type(P>0.05).Conclusion:1.Large area cerebral infarction and cortical infarction are independent risk factors for epilepsy secondary to cerebral infarction.2.large atherosclerotic cerebral infarction,large area cerebral infarction is likely to lead to delayed seizures.