The Influence Of Different Body Temperatures During Surgery On Tranexamic Acid Hemostatic Effect In Patients With Total Hip Arthroplasty

Objective:To investigate the influence of different body temperatures during surgery on tranexamic acid hemostatic effect in patients with total hip arthroplasty.Methods:Selected from November 2016 to September 2018 in guangxi zhuang autonomous region people's hospital of 60 patients with primary unilateral total hip arthroplasty,were randomly divided into two groups,30 patients each group.Temperature intervention group maintains the temperature of patients more than 36? by preheating input liquid,controllable thermal insulation blanket and regulate the operating room environment temperature.Control group don't do special temperature protection.Patients in the two groups were intravenous drip of 1.0g tranexamic acid within 30 minutes before surgery,and then intravenous drip of 1.0g tranexamic acid again 3 hours after the first use of tranexamic acid.Perioperative blood loss,postoperative hemoglobin content and the number of blood transfusions were compared between the two groups.Result:The average temperature of the intervention group was higher thanthat of the control group,the difference was statistically significant(P < 0.05).Intraoperative blood loss and postoperative blood loss and recessive blood loss volume in the temperature intervention group were both lower than those in the control group,and the differences were statistically significant(all P<0.05).The Hemoglobin concentrations of patients from temperature intervention group is higher than that of patients from control group,and the difference is significant(P < 0.05).The number of blood transfusion and transfusion rate temperature intervention group was obviously less than control group,the difference was statistically significant(P < 0.05).Conclusion:Hypothermia during total hip arthroplasty can reduce the hemostatic effect of tranexamic acid,while maintaining normal body temperature during surgery can more effectively reduce the intraoperative and postoperative blood loss and recessive blood loss,and reduce the transfusion rate.