Kidney Drain Turbidity Middle Invigorate The Circulation Of The Treatment Of Chronic Renal Failure Clinical Observation

Objective:To explore the clinical efficacy of the treatment of patients with chronic renal failure in the treatment of chronic renal failure with the treatment of patients with chronic renal failure,and to provide evidence of efficacy and safety for the treatment of chronic renal failure.Methods:Combine traditional Chinese and western medicine hospital in Shanxi Province,72 patients with chronic renal failure early and mid-term as the research object,the patients are all combine traditional Chinese and western medicine hospital urology department in hospital and outpatients in shanxi,and conforms to the inclusion criteria and voluntarily to participate in this study,were randomly divided into two groups,36 cases in each group.Patients in all groups were given routine treatment of chronic renal failure in western medicine,low salt,low fat and high quality low protein diet.Improve microcirculation,correct anemia and water,electrolyte,acid and alkali imbalance,as well as control blood pressure,control infection,diuretic swelling and other symptomatic treatment.The control group gave western medicine routine treatment and kidney failure ning capsule,efficacy:yiqi jianpi,invigorate blood and blood stasis,and turbidity;Production batch no.:Z53021547,specification: 0.35g;Five tablets at a time,three times a day;Treatment group on the basis of conventional western medicine treatment,jiayi renal drainage turbidity huoxue fang(radix astragali 30 g,rhizoma ligustici wallichii,15 g angelica 15 g,12 g,peach kernel,safflower,12 g,salvia miltiorrhiza 30 g,prepared rhizome of rehmannia,15 g rhubarb charcoal 10 g,12 g,poria cocos,semen plantaginis 30 g,talc 30 g,pinellia 12 g,gun nail bead,20 g dried tangerine or orange peel 10 g,licorice root 6 g);We use the granule free granules,and each time,one bag at a time.The preparation of traditional Chinese medicine is completed and provided by the preparation room of our hospital.Both groups were observed for 4 weeks.To observe and compare the two groups of patients before and after treatment,serum creatinine(Scr),endogenous creatinine clearance rate(Ccr),blood urea nitrogen(BUN),24-hour urine protein(24h-Upro)and quantitative changes before and after treatment of Chinese medicine symptom integral,and analyze the two groups of efficacy and safety evaluation.Results:1.Efficacy evaluation: the total effective rate of the treatment group and the controlgroup was(91.6%)and(72.2%),and the difference was statistically significant(P < 0.05).The total effective rate of TCM syndromes in the treatment group and the control group was(94.4%)and(77.7%),and the difference was statistically significant(P < 0.05).After treatment,the scores of TCM syndromes in both groups changed,and the difference between the two groups was statistically significant,P < 0.05;2.Laboratory indicators: before the treatment,two groups of serum creatinine(Scr),endogenous creatinine clearance rate(Ccr),blood urea nitrogen(BUN),24-hour urine protein quantitative(24 h-Upro)level differences had no statistical significance(P > 0.05);After treatment,two groups of serum creatinine(Scr),24-hour urine protein quantitative(24 h-Upro),blood urea nitrogen(BUN)level decreased,compared with before treatment(P < 0.05),treatment group decreased levels lower than the control group(P < 0.05);After treatment,two groups of endogenous creatinine clearance rate(Ccr)levels were increased,compared with before treatment(P < 0.05),the treatment group the endogenous creatinine clearance(Ccr)level is better than that of control group(P < 0.05);3.Safety assessment: there were no four adverse reactions in the treatment group and the control group,and there was no statistically significant difference in the safety indicators(P < 0.05).Conclusion:It is safe and effective for both kidney and kidney failure.Treatment group in patients with lower serum creatinine(Scr),blood urea nitrogen(BUN),24-hour urine protein quantitative(24 h-Upro)level,improve the patients' endogenous creatinine clearance(Ccr),improve the symptoms of traditional Chinese medicine is better than that in control group,treatment group,in improving renal function,delay the progress of the renal failure is better than the control group.