The Value Of ABCD2 Score In Predicting Moderate-to-Severe Cerebral Arterial Stenosis In Patients With Minor Ischemic Stroke

Objective To investigate the value of ABCD2 score in predicting moderate-to-severe cerebral arterial stenosis（CAS）in patients with minor ischemic stroke（MIS）.MethodsA total of 402 patients with acute MIS（national institute of health stroke scale,NIHSS score≤5）were selected as subjects.The ABCD2 score was obtained in the acute phase and the situation of CAS was detected by head and neck computed tomography angiography（CTA）.The vascular stenosis≥50%was set to the moderate-to-severe CAS group and according to the location,extent,and extent of the CAS,CAS was divided into the intracranial and/or extracranial,anterior and/or posterior circulation,moderate（50%-69%）,severe stenosis or occlusion（≥70%）and single or multiple stenosis.these data was analyzed using statistics.Results Among the 402 cases of MIS,220 cases had moderate-to-severe CAS（54.73%）.Among them,125 cases（56.82%）had intracranial stenosis.55 cases（25%）had extracranial stenosis.40 cases（18.18%）had cranial-inside and external stenosis.108 cases（49.09%）had anterior circulation stenosis.65 cases had posterior circulation stenosis（29.55%）.47 cases（21.36%）had anterior-posterior circulation stenosis.63 cases（28.64%）had moderate stenosis.157 cases（71.36%）had severe stenosis or occlusion.92 cases（41.82%）had single stenosis.128 cases（58.18%）had multiple stenosis.The ABCD2 score predicts the intracranial,anterior circulation,severe,and multiple stenosis Receiver Operating Characteristic（ROC）curves showing the area under the curve（AUC）:AUC_{（intracranial）}=0.552,95%CI is 0.495⁰.608,P=0.078,AUC_{（anterior circulation）}=0.561,95%CI is 0.504⁰.618,P=0.040,AUC_（severe）=0.586,95%CI is 0.530⁰.642,P=0.003,AUC_{（multiple）}=0.553,95%CI is 0.493⁰.614,P=0.085.The proportion of moderate-to-severe CAS in the 4⁷ group of ABCD2 score was significantly higher than that in the 0³ group.The difference was statistically significant（χ2=4.926,P=0.026）,and the degree of CAS increased with the increase of the risk level of ABCD2（r_s=0.102,P=0.040）.ConclusionMore than half of MIS patients have moderate and upper large vessel stenosis,mainly intracranial,anterior circulation,severe and multiple stenosis.The ABCD2 score has a certain value in predicting the location and extent of CAS in MIS patients.