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The Value Of ABCD2 Score In Predicting Moderate-to-Severe Cerebral Arterial Stenosis In Patients With Minor Ischemic Stroke

Posted on:2020-05-17Degree:MasterType:Thesis
Country:ChinaCandidate:Y XiaFull Text:PDF
GTID:2404330575487658Subject:Neurology
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Objective To investigate the value of ABCD2 score in predicting moderate-to-severe cerebral arterial stenosis?CAS?in patients with minor ischemic stroke?MIS?.MethodsA total of 402 patients with acute MIS?national institute of health stroke scale,NIHSS score?5?were selected as subjects.The ABCD2 score was obtained in the acute phase and the situation of CAS was detected by head and neck computed tomography angiography?CTA?.The vascular stenosis?50%was set to the moderate-to-severe CAS group and according to the location,extent,and extent of the CAS,CAS was divided into the intracranial and/or extracranial,anterior and/or posterior circulation,moderate?50%-69%?,severe stenosis or occlusion??70%?and single or multiple stenosis.these data was analyzed using statistics.Results Among the 402 cases of MIS,220 cases had moderate-to-severe CAS?54.73%?.Among them,125 cases?56.82%?had intracranial stenosis.55 cases?25%?had extracranial stenosis.40 cases?18.18%?had cranial-inside and external stenosis.108 cases?49.09%?had anterior circulation stenosis.65 cases had posterior circulation stenosis?29.55%?.47 cases?21.36%?had anterior-posterior circulation stenosis.63 cases?28.64%?had moderate stenosis.157 cases?71.36%?had severe stenosis or occlusion.92 cases?41.82%?had single stenosis.128 cases?58.18%?had multiple stenosis.The ABCD2 score predicts the intracranial,anterior circulation,severe,and multiple stenosis Receiver Operating Characteristic?ROC?curves showing the area under the curve?AUC?:AUC?intracranial?=0.552,95%CI is 0.4950.608,P=0.078,AUC?anterior circulation?=0.561,95%CI is 0.5040.618,P=0.040,AUC?severe?=0.586,95%CI is 0.5300.642,P=0.003,AUC?multiple?=0.553,95%CI is 0.4930.614,P=0.085.The proportion of moderate-to-severe CAS in the 47 group of ABCD2 score was significantly higher than that in the 03 group.The difference was statistically significant??2=4.926,P=0.026?,and the degree of CAS increased with the increase of the risk level of ABCD2?rs=0.102,P=0.040?.ConclusionMore than half of MIS patients have moderate and upper large vessel stenosis,mainly intracranial,anterior circulation,severe and multiple stenosis.The ABCD2 score has a certain value in predicting the location and extent of CAS in MIS patients.
Keywords/Search Tags:minor ischemic stroke, cerebral arterial stenosis, ABCD2 score
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