The Value Of ABCD2-â…  And ABCD3-â…  Score In Predicting The Risk Of Stroke After Transient Ischemic Attack

Background Transient ischemic attack (TIA) is episode of reversible of neurologicdeficit caused by temporary focal central or retinal hypoperfusion. TIA is a medicalemergency, and is associated with high risk of early recurrent stroke, particularly withinthe first48hours of TIA. In some studies, TIA is associated with stroke rates as high as35%by7days, and the risk of recurrent TIA, myocardial infarction and death within90days is also high. Therefore, the evaluation of TIA and effective intervention are pivotal toprevent a disabling stroke.Objective To study the clinical value of ABCD2-I and ABCD3-I score inevaluating the early risk of stroke after transient ischemic attack (TIA).Methods The clinical data and imaging data of154consecutive patients with TIAwere collected in this research. All patients were evaluated according to ABCD2,ABCD2-I, ABCD3, ABCD3-I criteria. The predictive power of prognostic scores weredetermined by using area under receiver operator characteristic curve (AUC) analysis, andcompared with the values between ABCD2-I score and ABCD3-I score in predicting earlystroke risk after TIA.Results Twelve TIA patients (7.8%) developed ischemic stroke within7days andnineteen (12.3%) within90days in154patients. All patients were divided into low riskgroup (0-3scores), moderate risk group(4-7scores) and high risk group(8-13scores). Theincidence of secondary cerebral infarction was significantly higher in high risk group thanin low and high risk group within7and90days (P<0.01). When the occurrences of strokewere observed in7days, the AUC of ABCD2, ABCD2-I, ABCD3, ABCD3-I scores were0.733,0.898,0.830,0.935; in90days, the AUC were0.699,0.857,0.778and0.906. ConclusionsABCD3-I score was more accurate in predicting early risk of stroke after TIA thanABCD2-I score, and had higher clinical value.