The Correlation Between Obstructive Sleep Apnea-hypopnea Syndrome (Osahs) And Blood Coagulation Function

Objective:Discussing the correlation between the obstructive sleep apnea-hypopnea syndrome(OSAHS)and blood coagulation function.Methods:Chose patients who had sleep snoring and suppressing breath waking presenting in our hospital between January 2015 and January 2018,120 cases of patients with OSAHS as experimental group.Chose another 40 patients with the vocal cord polyp presenting in the hospital in the same period,with matching age and gender of the experimental group as a control group.All the patients in the control group showed no significant sleep snoring and breath suppressing symptoms.Tested lines of routine blood,the blood coagulation and polysomnography for all patients in both groups.Selected coagulation function related indicators to further statistical analysis.In this experimental comparation,the blood coagulation function indicators included platelet distribution width(PDW),mean platelet volume(MPV),platelet accumulation(PCT),blood platelet(PLT),prothrombin time(PT),activated partial thromboplastin time(APTT),thrombin time(TT),and fibrinogen(FIB).During the experiment,relevant indicators of OSAHS contained body mass index(BMI),and apnea hypopnea index(AHI).Based on the results of the AHI studying,further divided the patients in the experimental group into three sub-groups,namely the mild group(5?AHI?15 times/h).the moderate group(15?AHI?30 times/h)and the severe group(AHI>30 times/h).Randomly selected 40 patients from the experimental group as sample group.Results:1.Comparing with the control group,PCT results of the moderate experimental groups was significantly higher than those in control group,which was a statistical difference(P<0.05).(Figure 1)2.Comparing with the control group,PLT results of the mild and moderate experimental groups were significantly higher than those in control group,which was a statistical difference(P<0.05).(Figure 2)3.Comparing with the control group,FIB results of the mild?moderate and severe experimental groups were significantly higher than those in control group,which was a statistical difference(P<0.05).(Figure 3).4.Comparing with the control group,PT results of the mild experimental group was significantly lower than the normal group(P<0.01).PT results of the severe experimental group was significantly lower than the normal group(P<0.05),which was a statistical difference.(Figure 4)5.Comparing with the control group,APTT results of the severe experimental group was significantly higher than those in control group(P<0.05).Comparing with the mild experimental group,APTT results of severe experimental group was significantly higher than those in the mild experimental group(P<0.001),which was a statistical difference.(Figure 5)6.According to the results of indicators in terms of PDW,MPV,and TT,there were no statistical significance between the experimental group and the control group.Conclusion:1.Patients with OSAHS reveal a hypercoagulable state.2.Indicator of blood coagulability is positively correlated with the severity of OSAHS.