| Purpose :In this study,we investigated the constitutional status of patients with type 2 diabetes mellitus(T2DM)in two different communities in Kunming,including their living environment,occupational characteristics,dietary habits and lifestyle,and comprehensively analyzed the forming factors of the constitutional differences of type 2 diabetes mellitus in the two communities based on the collected data and laboratory examinations.To explore the inherent law of the development of TCM constitution and type 2 diabetes mellitus,provide theoretical basis for community residents to improve TCM constitution,prevent and treat diseases,and also provide certain reference and guidance for hospitals and community health service departments in Kunming to prevent and treat type 2 diabetes mellitus.Method:In this study,the epidemiological cross-sectional study of type 2 diabetes mellitus patients in Kunming Union Community and Majinpu Community was conducted by means of clinical questionnaires.The general information of the patients was collected,including name,sex,age,height,weight,body mass index(BMI),course of disease,educational level,family history and dietary habits.The clinical indicators included blood pressure(b).Lood pressure,BP,Fasting plasma glucose(FPG),Triglycerides(TG),Total Cholesterol(TC)and so on,and to understand the environment,landscapes,customs,dietary habits,occupational characteristics and lifestyle of their communities,fill in questionnaires on TCM constitution determination,and use SPSS22.0 to collect all the information.Statistical analysis was carried out to compare the differences of TCM physique between the two communities with type 2 diabetes mellitus,and to analyze and study the related factors of the differences.Result:1.A total of 502 patients with T2 DM who met the inclusion criteria were collected,including 279 in the Alliance Community and 223 in the Majinpu community.2.The age of patients with T2 DM in the two communities was mainly over 60 years old.The age of patients in the alliance community was significantly higher than that in the Majinpu community,the course of disease was longer than that in the Majinpu community,and the TCHO level was higher than that in the Majinpu community,but the BMI level was lower than that in the Majinpu community,with significant statistical significance(P < 0.01).Majinpu community is mainly concentrated in primary schools and junior middle schools,with significant statistical significance(P < 0.01);more than half of the sick people in the alliance community are mainly on balanced diet;the eating habits of the sick people in the Majinpu community are salty and biased,and the proportion of balanced diet is lower than that in the alliance community,with significant statistical significance(P < 0.01);most of the sick people in the two communities are on balanced diet(P < 0.01).There was no family history.In addition,there was no significant difference in systolic blood pressure,diastolic blood pressure and TG levels(P > 0.05).3.Among the patients in the alliance community,the top five single constitutions are: phlegm-dampness,yin-deficiency,yang-deficiency,qi-deficiency,blood stasis and peace;among the patients in Majinpu community,the top five single constitutions are: peace,phlegm-dampness,yin-deficiency,Qi-deficiency and blood stasis.The top three concurrent constitutions in the two communities are the same.They are: concurrent constitution with Qi deficiency,phlegm and dampness,and concurrent constitution with blood stasis.Among them,the most important types are: Qi deficiency + Yin deficiency,Qi deficiency + phlegm and dampness.4.Comparison of gender in different constitutional types of patients with T2 DM in the two communities: The proportion of men in the Alliance Community in the constitution of peace and Qi deficiency is less than that in Majinpu community,and the difference is statistically significant(P < 0.05).The age of patients with type 2 diabetes mellitus in two communities was compared in different constitution types: the average age of patients with type 2 diabetes mellitus in alliance community was higher than that in Majinpu community(P < 0.05);the age of patients with type 2 diabetes mellitus in alliance community was higher than that in Majinpu community(P < 0.05).The comparison of educational level of patients with T2 DM in two communities in different constitution types: phlegm-dampness,blood-stasis,calm,Qi-deficiency,phlegm-dampness and blood-stasis(P < 0.05).Comparisons of the course of T2 DM patients in two communities in different constitutional types: Except for blood stasis and calm constitution,the difference of other constitutional courses is statistically significant,and the course of blood stasis combined with constitution is the longest(P < 0.05).The dietary habits of patients with type 2 diabetes in two communities were compared in different constitutional types.There was significant statistical significance between the dietary habits of patients with type 2 diabetes who had Yin deficiency and Qi deficiency as the main components(P < 0.01).The BMI of patients with T2 DM in two communities in different constitution types were compared: the difference of BMI between patients with calm constitution and those with both Qi deficiency constitution was statistically significant(P<0.05);in addition,the BMI of patients with both phlegm and dampness constitution in alliance community was the highest,while that of patients with T2 DM in Majinpu community was the highest,with significant difference(P<0.05);The comparison of fasting blood glucose in different constitutional types of patients with T2 DM in two communities: phlegm-dampness,calm,Qi-deficiency and phlegm-dampness(P < 0.05).Comparison of TG and TCHO in different constitutional types of patients with T2 DM in two communities: There was no significant difference between TG in different constitutional types(P > 0.05);there was significant difference between TCHO in Yin deficiency,phlegm-dampness,Qi deficiency,phlegm-dampness and blood stasis(P < 0.05).5.Qi deficiency is negatively correlated with gender(male)(OR=0.537,P=0.004);it is positively correlated with education level of primary school and below,junior high school and senior high school(secondary school)(OR=3.106,3.251,3.576,P=0.047,0.037,0.029);it is positively correlated with eating habits of sweetness,saltiness and spicy(OR=2.513,1.839,2.417,P=0.010,0.022,0.024);6.Yin deficiency was negatively correlated with BMI(OR=0.875,P=0.000),and positively correlated with sweeter and hotter eating habits(OR=2.310,4.404,P=0.0021,0.000).7.The phlegm-dampness quality was positively correlated with BMI and sweeter eating habits(OR = 1.481,3.141,P = 0.000,0.004).8.Yang deficiency was negatively correlated with BMI(OR=0.894,P=0.018).9.Blood stasis was positively correlated with age(OR=1.046,P=0.002).10.Gender(male)was positively correlated with gender(OR=2.769,P=0.004).Conclusion:1.The fasting blood glucose level of patients with T2 DM in alliance community is better than that in Majinpu community,but TCHO level is not as good as that in Majinpu community.2.The high-incidence constitutions of patients with T2 DM in Alliance Community are: phlegm-dampness,yin-deficiency,yang-deficiency,Qi-deficiency and blood-stasis.The high-incidence constitutions of patients with T2 DM in Majinpu community are calm,phlegm-dampness,yin-deficiency,Qi-deficiency and blood-stasis.The high-incidence constitutions of both communities are the same,which are the combination of qi-deficiency,phlegm-dampness and blood-stasis,respectively.The highest proportion of them are Qi deficiency + Yin deficiency,Qi deficiency + phlegm dampness.3.Gender,age,educational level,dietary habits and BMI are the factors influencing the formation of biased constitution in patients with T2 DM.Among them,the dietary habits of elementary school and below,junior high school and senior high school education,sweetness,saltiness and spicy are the risk factors of deficiency of qi,while gender(male)is the protective factor of deficiency of qi;sweetness and spicy dietary habits are the risk factors of deficiency of yin,while BMI is the protective factor of deficiency of yin;BMI and sweetness dietary habits are the risk factors of phlegm-dampness;BMI is the protective factor of deficiency of yang.Age is the risk factor of blood stasis.4.Gender(male)is the influencing factor of calm quality of T2 DM. |
PDF Full Text Request