The Risk Factor Analysis Of Anxiety And Depression Among Refractory Epilepsy

Objective: Refractory epilepsy patients are easily to complicate with psychological and mental disease during the long suffering time,the manifestation of anxiety or depression is the most common complications.This article aims to discuss the risk factor of anxiety and depression among refractory epilepsy patients,making patients not only to concentrate on their seizure status but their psychological and mental health should be taken into consideration,moreover it must be diagnosed and treated earlier in order to improve quality of life and prognosis.Method: The refractory epilepsy patients in our hospital epilepsy center were collected from March 2010 to March 2018 as samples for this study.Estimate them with Beck depression questionnaire and Hamilton anxiety scale according to their realistic situation,their age,education background,duration of disease,seizure frequency,seizure type,way of treatment,atrophy of hippocampus,depression and anxiety of family guardian were asked as potential risk factor,the above factors were analyzed by chi-square test and binary logistic analysis using SPSS 25,P<0.05 has statistical significance,summarize the meaningful risk factors of anxiety and depression among refractory epilepsy patients.Result: 62 refractory epilepsy patients involved in this study,42 patients(67.7%)are annoyed by depression,48 patients(77.4%)for anxiety.The cases are divided into depression group and non-depression group,anxiety group and non-anxiety group respectively.The patients’ seizure frequency,seizure type,atrophy of hippocampus,way of treatment,depression of family guardian have statistical significance with theircomplicated depression;seizure frequency,seizure type,atrophy of hippocampus are related to complicated anxiety analyzed by chi-square test.Seizure frequency,seizure type,atrophy of hippocampus,way of treatment are related to complicated depression;atrophy of hippocampus have statistical significance with complicated anxiety analyzed by binary logistic analysis.Conclusion: 1.Frequently seizure,general seizure,hippocampus atrophy are risk factors of depression in refractory epilepsy patients;hippocampus atrophy is risk factor of anxiety in refractory epilepsy patients.2.Refractory epilepsy patients treated only by pharmaceutical drug are vulnerable to depression compared to patients treated by surgery and drug.3.Depression of family guardian have a robust impact on refractory epilepsy patients,but anxiety of family guardian don’t have the former influence.