Research Of YE Tian-shi's And Prof.Gao Jing-dong's Herb-using Regulation In Dysphagia Based On Data Mining

Objective:To research the herb-using regulation in dysphagia of YE Tian-shi and Gao Jing-dong.Methods:Collect the cases in YE's and Prof.Gao's medical records.Extract the herbs from those cases and process them with data mining methods,including frequency analysis,cluster analysis,with EXCEL2013,SPSS22.0 and other software.Results:YE's part:Analysis of herb frequency,herb efficacy,flavor and meridian tropism:high-frequency herbs in the case of dysphagia from YE Tian-shi are:rhizoma pinelliae(11.8%),Poria cocos(Schw.)Wolf(10.8%),rhizoma zingiberis recens(8.8%),rhizoma coptidis(6.4%),radix ginseng(5.4%),etc.The top five categories of herb efficacy were:herbs resolving phlegm and relieving cough and asthma(28.4%),herbs for deficiency syndromes(12.3%),herbs for relieving exterior syndromes(11.8%),herbs for regulating qi(11.3%)and herbs for diuresis and diffusing dampness(11.3%).Bitter,acrid and sweet are the most used traditional chinese medicine flavors.Warm herbs and cold herbs are common used.Most medicine are beneficial to lung,spleen and stomach.(2)Based on the cluster analysis,high-frequency herbs can be divided into four groups:C1:Evodia rutaecarpa(Juss.)Benth.,pericarpium citri reticulatae viride,flos inulae,ocherum rubrum,Succus Bambusae(Recens),radix platycodi,rhizoma zingiberis recens,rhizoma pinelliae,rhizoma coptidis,fructus aurantii immaturus,Poria cocos(Schw.)Wolf;C2:rhizoma zingiberis,radix aconiti lateralis preparata,radix ginseng,rhizoma alismatis,radix aucklandiae,radix angelicae sinensis,fructus amomi amari,pericarpium citri reticulatae,Eugenia aromatica Kuntze;C3:colla corii asini,bulbus fritillariae cirrhosae,fructus mume,radix paeoniae alba,gypsum fibrosum,radix glycyrrhizae,fructus cannabis,folium mori,rehmannia dride rhizome,Radix Ophiopogonis Japonici,semen platycladi,rhizoma polygonati odorati,radix asparagi,semen armeniacae amarum,ramulus cinnamomi;C4:flos carthami,Rhizoma Corydalis Yanhusuo,fructus meliae toosendan,radix curcumae,semen persicae,Fructus et Semen Trichosanthis Kirilowii,exocarpium citri rubrum,Semen Sojae Praeparatum,fructus gardeniae,rhizoma cyperi,radix asteris,fructus perillae,folium eriobotryae,fructus aurantii,radix et rhizoma rhei.Gao's part:Analysis of drug frequency,drug efficacy,flavor and meridian tropism:high-frequency drugs in the case of dysphagia from Gao Jing-dong are:Tangerine Peel(73.5%),Pinellia Tuber(69.4%),Poria Cum Radix Pini(65.3%),Cortex Albiziae(60.2%),Corydalis Rhizoma(56.1%),etc.The top five categories of drug efficacy were:drugs for deficiency syndrome(19.3%),drug for invigorating blood circulation and eliminating stasis(11.3%),drugs for diuresis and diffusing dampness(9.5%),drugs for regulating qi(9.2%)and drugs resolving phlegm and relieving cough and asthma(8.9%).Sweet,bitter and acrid are the most used traditional Chinese medicine flavors.Warm herbs,mild herbs and cold herbs are common used.Most medicine are beneficial to spleen,liver and lung.Based on the cluster analysis?high-frequency herbs can be divided into four groups:C1:herba cistanches,radix achyranthis bidentatae,semen armeniacae amarum,semen persicae,semen cassiae,Fructus et Semen Trichosanthis Kirilowii,radix rehmanniae,rhizoma polygoni cuspidati,Chinese eaglewood medicated leaven,buthus martensi,radix salviae miltiorrhizae,rhizoma anemarrhenae,semen citri reticulatae,radix panacis quinquefolii,cortex moutan radicis,retinervus luffae fructus,fructus aurantii immaturus,Magnolia officinalis Rahd.et Wils.,Rhizoma Corydalis Yanhusuo,rhizoma cyperi,Radix Ophiopogonis Japonici,herba dendrobii,radix paeoniae alba,betelnutpalm pericarp,rhizoma atractylodis macrocephalae;C2:pseudobulbus cremastrae seu pleiones,herba taraxaci,radix pseudostellariae,rhizoma curcumae,Poria cocos(Schw.)Wolf,radix angelicae sinensis,fructus lycii,prunella vulgaris 1.,radix scutellariae,concha ostreae,Fossilia Ossia Mastodi,bulbus fritillariae cirrhosae,radix paeoniae rubra,L.brownii var.colchesteri(Van Houtt.)Wils.ex Elwes,caulis spatholobi,Poria Cum Radix Pini,fructus ligustri lucidi,carapax trionycis,Loranthus chinensis DC,,nidus vespae,semen cuscutae,Radix seu Herba Cynanchi Paniculati,radix actinidiae chinensis,fructus citri sarcodactylis,fructus hordei germinatus;C3:herba ecliptae,herba agrimoniae,fructus schisandrae chinensis,Radix Palygalae,semen ziziphi spinosae,cortex albiziae,cortex mori,Faeces Togopteri,pollen typhae,radix bupleuri,rhizoma dioscoreae,rhizoma curcumae longae,herba asari,boswellia carterii,aspongopus chinensis dallas,fructus liquidambaris,fructus crataegi,L.sinense Oliv.cv.Chuanxiong,endothelium comeum gigeriae galli,rhizoma pinelliae,pericarpium citri reticulatae,atractylodes chinensis,rhizoma coptidis,fructus amomi,Agastache rugosa(Fisch.et Mey.)O.Kuntze,massa medicata fermentata,rhizoma zingiberis.Conclusion:Ye Tian-shi paid attention to physical and mental recuperation when treating the dysphagia.According to the characteristics of the disease,choose the cold or hot medicine flexibly,pay attention to the recuperation of the lung,spleen,stomach and other organs,use traditional Chinese medicine of resolving phlegm and relieving cough and asthma,and implement the method of opening with acrid agents and descending with bitter agents.Pay attention to warm Yang,use ginger in many ways,especially ginger juice.He created a new method to treat the dysphagia:pay attention to the body fluid of lung and stomach,be careful with traditional Chinese medicine which are easy to consume the body fluid,be careful when using glycyrrhiza.Based on Ye's methods,Prof.Gao tends to balance Yin and Yang.Use stomachic herbs to regulate qi-flowing for eliminating phlegm,along with cold herbs to nourish.Especially pay attention to improve patients' life quality by regulating qi to alleviate pain,enriching the blood and moisturizing the intestine and calming nerves.