The Clinical Study On Improving The Clinical Efficacy Of Chronic Atrophic Gastrotis With Erosive Spleen-stomach Deficiency Syndrome And The Influence Of PG?,PG? And G-17

Objective:Observe the endoscopic,pathological improvement,clinical symptoms and the effect on PG?,PG ?,G-17 in patients with CAG with erosive spleen-stomach deficiency syndrome treated by warming stomach.Methods:Select 108 patients with chronic atrophic gastritis with erosive spleen-stomach deficiency syndrome in accordance with the inclusion criteria,divided into 54 cases in the treatment group aind 54 cases in the control group,the control group was treated with weifuchun tablet,the treatment group was taken with stomach warming decoction,6 months of treatment.The endoscopic,pathological improvement,clinical symptoms and the effect on PG I,PG II,G-17 of the two groups were observed before and after treatment.The curative effect was also evaluated by statistical analysis.Results:In the efficacy of traditional Chinese medicine syndrome:The total effective rate of the treatment group was 92.59%.The total effective rate of the control group was 68.52%.The difference between the two groups was statistically significant(P<0.01).The total score of the clinical symptoms:The total score of the clinical symptom after treatment in the control group and the treatment group was significantly lower than that before the treatment(P<0.01).Comparing the two groups,the total score of clinical symptom after treatment in the treatment group was significantly lower than that of the control group(P<0.01).In terms of traditional Chinese medicine symptom scores:There were five aspects of stomachache,sour regurgitation,fullness in the stomach,dry and bitter mouth,poor appetite.The treatment group was superior to the control group and the difference was statistically significant(P<0.01).Comparison of endoscopic erosion:The total effective rate was 50%in the control group and 90.74%in the treatment group.The difference between the two groups was statistically significant(P<0.01).Histopathological comparison:The reversal of gastric gland atrophy and intestinal metaplasia in the treatment group was better than the control group(P<0.01).The comparison of PG I,PG II and G-17 levels:There was difference between the treatment group and the control group in the improvement of PG I,PG II and G-17 levels(P<0.05).Conclusion:Warming-stomach method significantly improve pathological and clinical symptoms of patients with chronic atrophic gastritis with erosive spleen-stomach deficiency syndrome,and curative effect is superior to the control group of weifuchun,no adverse,safe and effective.