Study On Female Sexual Dysfunction And Its Influencing Factors Among Postoperative Patients With Breast Cancer At Childbearing Age

Objective To investigate the prevalence and risk factors of female sexual dysfunction(FSD)among postoperative patients with breast cancer at childbearing age,and to provide theory evidence for measurements intervention improving the sexual function of breast cancer survivors.Methods A convenient sampling method was conducted in a third-grade class-A hospital in Hefei city of Anhui province,and 249 paitients who were recruited from the department of tumor and radiation therapy diagnosed as postoperative of breast cancer patients at childbearing age(postoperative time > 2 weeks)from February 2017 to February 2018.They were investigated by the general information questionnaire,Female Sexual Function Index(FSFI),Social Support Rating Scale(SSRS)and Body Image Scale(BIS).The general information questionnaire included socio-demographic data,information on disease treatment and sexual rehabilitation.Epi Date 3.1 software and SPSS16.0 software were adopted.the incidence of FSD in patients with different characteristics were compared by two independent samples t-test or ?2 test.Pearson correlation analysis was used to explore the relationship between the incidence of FSD and the level of social support and body image.And the logistic regression analysis was carried out to explore the protective factors and risk factors of FSD.In the present study,the value less than 0.05 was considered to be statistically significant.Results(1)The total score of FSFI in the patients with breast cancer was(21.38 ± 8.12).The total and each dimension scores of FSTI were all lower than the norm in Chinese female population(P<0.05).The overall prevalence of FSD was 62.2%.And the prevalence of hyposexuality(?2=154.863,P<0.001),sexual arousal disorder(?2=111.878,P<0.001),virginal dryness(?2=8.848,P=0.003),orgasm disorder(?2=35.990,P<0.001)and low sexual satisfaction(?2= 26.800,P<0.001)were significantly higher than those in Chinese female norm(P<0.05).(2)Univariate analysis showed that:(1)Social demographic variables: the prevalence of FSD in patients with breast cancer were significant differences between different occupations(?2=21.820,P<0.001)and education(?2=13.791,P =0.003).(2)The information about disease treatment: there were significant differences in the incidence of FSD among breast cancer patients with different operative methods,postoperative time,whether recurrence or not,whether metastasis or not,whether or not recieve endocrine therapy and the most recent treatment methods(all P< 0.05).(3)The information about sexual rehabilitation: there were significant differences in the incidence of FSD among breast cancer patients with whether or not receive professional guidance on sexual life after operation,sought professional guidance on sexual life actively,learn about sexual life through non-professional personnel and the first sexual time after surgery,There was significant difference in the incidence of FSD in breast cancer patients(all P < 0.05).(3)Pearson correlation analysis showed that:(1)FSD and social support: there were significant positive correlations between the total or each dimension of FSD and the total or objective or subjective of social support in breast cancer patients(r=0.127~0.386,all P<0.05);there was correlation between sexual arousa and utilization of social support(r=0.129,P<0.05);there was correlation between sexual life satisfaction and utilization of social support(r=0.161,P<0.05).(2)FSD and body image level: there were significant correlations between the total or each disorder dimension of FSD and the total or each dimension of BIS in breast cancer patients,the correlation coefficients were range-0.426 to-0.706,all P< 0.05.(4)Logistic regression analysis showed that: the postoperative time(OR=0.212,95%CI:0.063-0.715,P=0.012),No endocrine therapy(OR=0.334,95%CI:0.149-0.749,P=0.008)and social support(OR=0.213,95%CI:0.074-0.612,P=0.004)are protective factors of FSD.No professional guidance on sexual life(OR=5.409,95%CI:2.233-13.103,P<0.001),the first sexual time after surgery(OR=11.256,95%CI: 1.761-71.941,P=0.011)and body image level(OR=22.920,95%CI:1.866-281.580,P=0.014)were risk factors of FSD.Conclusion The prevalence of FSD is higher in patients with breast cancer at childbearing age.The factors such as postoperative time,endocrine therapy,professional guidance of sexual life,recovery time of postoperative sexual life,the level of social support and body image may be influencing factors of FSD.