TCM Syndromes Of Obstructive Sleep Apnea-hypopnea Syndrome Research On Stratification Of Age

ObjectiveThis study analyzed the clinical data of young and middle-aged and elderly obstructive sleep apnea-hypopnea syndrome patients who were admitted from September 2016 to January 2018 in the integrated tertiary department of the University Hospital of Guangdong Provincial Hospital of Traditional Chinese Medicine to discuss the characteristics and rules of TCM syndrome distribution.MethodsThe clinical epidemiology investigation method is used in this study,a total of 135 patients who met the inclusion criteria were collected,and the information of TCM syndromes was collected by filling out the information questionnaire formulated in advance.The collected information was built with Excel software and SPSS 17.0 software was used for statistical analysis.Results1.Epidemiological survey results(1)The young and middle-aged gnoup collected 66 cases of OSAHS patients,57 males,accounting for 85.1%,10 females,accounting for 14.9%.The elderly group collected 69 cases.54 were males(79.4%),and 14 were females(20.6%).(2)The youngest patients were 23 years old.The olderest patients were 92 years old.The largest number of age distribution ranged from 50 to 80 years old.51-60 years and 61-70 years respectively has 29 patients,each accounting for 21.48%.A total of 20 cases aged 71-80 years,accounting for 14.81%of total cases.A total of 18 cases aged 81-90,accounting for 13.33%of the total number of cases.The average age of young and middle-aged group was 49.15±8.05,and the average age of the elderly group was 73.65±8.39,(3)The average BMI index of the young and middle-aged group was 27.31±5.93,of which 67.65%was higher than the normal range.The average BMI for the elderly group was 26.02±4.42,of which 66.67%was higher than the normal range.(4)In the young and middle-aged group,35 cases were mild cases(52.24%),16 cases were moderate cases(23.88%)and 16 cases were severe cases(23.88%).The average AHI index of middle-aged and young groups was 23.14±20.09.In the elderly group,24 cases were mild patients,with 35.29%of the proportion,22 cases were moderate patients,with 32.35%of the proportion and 22 cases were severe patients,with 22.35%of the protortion.The average AHI index of the elderly group was 26.78±17.12.(5)In the young and middle-aged group,26 cases were mild hypoxia,20 cases were severe hypoxia,and 21 cases were moderately hypoxicj,each accounting for 38.81%,31.34%,29.85%.The average of the minimum SaO2%was 81.57±7.6.While in the elderly group,17 cases were mild hypoxic patients,27 cases were moderate hypoxia,Severe hypoxia patients were 24 cases,each accounting for 25%,39.71%,35.29%.The average minimum Sa02%in the elderly group was 79.56±8.45.There was no statistically significant difference between the minimum SaO2%in both groups.(6)The average score of the ESS scale in the young and middle-aged group was 14.85+4.13.and was 17.13±3.31 in the elderly group.There was significant difference in ESS scores between the two groups.(7)There are more patients with high blood pressure(58.21%),hyperuricemia(64.18%),renal insufficiency(50.75%),and diabetes(40.30%)in the young and middle-aged group.Elderly patients had more hypertension(70.59%),hyperuricemia(48.53%),diabetes(41.18%),renal insufficiency(38.24),and coronary heart disease(32.35%).Hypertension,hyperuricemia,renal insufficiency,and diabetes were the common comorbidities in both groups.2.The characteristics of TCM syndromeAmong the young and middle-aged group,the largest number of people are phlegm dampness syndrome,with 56.72%of the proportion,followed by the phlegm heat,with 17.91%of the proportion.The overall case is sthenia syndrome.Among the elderly group,the largest number of people are lung and spleen-qi deficiency syndrome,with 47.06%of the proportion,followed by the phlegm dampness syndrome,accounting for 33.82%.3.The distribution of symptoms and signs in TCMA total of 16 clinical symptoms were collected,including snoring,dry mouth,drowsiness during daytime,poor sleep quality,nocturnal awakening,headache,numbness of the extremities,palpitations,constipation,chest tightness,edema,shortness of breath,excessive urination,difficulty in urinating,and abdominal distension.Among them,the frequency more than 25%was seen as the main symptom,and the secondary symptom.was the frequency between 10%and 25%.The main symptoms of the two groups were both shown as snoring(111 cases,82%),dry mouth(104 cases,77%),drowsiness during daytime(113 cases,84%),poor sleep quality(88 cases,65%),headache(50 cases,37%),and excessive urination(46 cases,35%).The secondary symptoms were both shown as nocturnal awakening(26 cases,19%),numbness of limbs(24 cases,18%),constipation(21 cases,16)%).For the elderly group,secondary symptoms also included difficulty in urination(12 cases,18%),shortness of breath(9 cases,13%),chest tightness(7 cases,10%),abdominal distension(7 cases,10%).ConclusionThe TCM syndrome types of obstructive sleecuapnea-hypopnea syndrome are mainly classified into six types,namely,phlegm dampness syndrome,dampness heat,blood stasis,qi stagnation,deficiency of lung and spleen qi,deficiency of kidney Yang syndrome.Among the young and middle-aged group,the largest number of people are phlegm dampness syndrome,and the overall cases were sthenia syndrome.While in the elderly group,lung qi deficiency syndrome was the most common syndrome type,and asthenia syndrome was the main type.