A Case-Control Study On Risk Factors Of Female Breast Cancer In Xinjiang

Objective: through epidemiological investigation and analysis,to explore the risk factors of breast cancer in Xinjiang women,and to provide a theoretical basis for breast cancer research and breast cancer prevention in Xinjiang.Methods: 318 cases of female breast cancer in Xinjiang and 318 non breast cancer patients at the same time were investigated by 1:1 case-control study.The matching factors were the same age group(? 3 years old),the same nationality,and the medical examination at the same time.The data were analyzed by chi-square test,t test,single factor and multi factor conditional logistic regression analysis.Results: the results of multivariate analysis showed that BMI is less than or equal to 24 as a reference,BMI=24-27.9(OR=3.111,95% CI=1.95~4.962),BMI =28(OR=5.681,95% CI=2.765~11.672),Contraceptive ring contraception(OR=,4.615,95%CI=2.993~7.116),The family history of breast cancer(OR=2.965,95% CI=1.077~8.167),Fat intake(OR=3.840,95% CI=1.615~9.131)related risk factors of female breast cancer incidence in Xinjiang,The monthly income of the family(OR=0.582,95% CI=0.348~0.971).Breast-feeding(OR=0.266,95% CI=0.146~0485),Three meals on time(OR=0.360,95%CI=0.181~0718),Menstruation span<35 years(OR=0.616,95% CI=0.394~0964)Protective factors related to the incidence of female breast cancer in Xinjiang.The risk factors associated with breast cancer in young women in Xinjiang are BMI(OR=4.603,95%CI=1638~12.934).Frequency of Abortion(OR=4.221,95%CI=1.943~9.168),Age of menarche(OR=3.628,95%CI=1.160~11.350),life stress(OR=2.718,95% CI=1.127~6.555),stay up late(OR=2.239,95%CI=1.149~4.720).The suitability of brassiere tightness(OR=00.050,95% CI=0.008~0.295)is a protective factor for breast cancer in young women in Xinjiang.Conclusion: The risk factors related to female breast cancer in Xinjiang area include BMI,contraceptive ring contraception,family history of breast cancer,and fat intake.The Family monthly income,breast-feeding,Menstruation span <35years and three meals on time are the protective factors for women's breast cancer inXinjiang.The risk factors related to the incidence of breast cancer in young women in Xinjiang are BMI,the age of menarche,the number of abortion,the life stress,and staying up late.The suitability of brassiere tightness is a protective factor for young women's breast cancer in Xinjiang.