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Study On The Quality(Grade)Standard Of Ginseng And Red Ginseng

Posted on:2020-12-13Degree:MasterType:Thesis
Country:ChinaCandidate:X DuFull Text:PDF
GTID:2404330572475927Subject:Pharmacy
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Objective:Ginseng is a treasure in Chinese herbal medicine.It is widely used in medicine and is world famous.Based on the existing legal ginseng and red ginseng quality standards in China compared with other countries,the TLC identification and content determination items are superior to other countries,but the inspection items are slightly lacking;the correlation between the classification of medicinal materials and quality and safety is not strong.And the quality evaluation criteria are missing,the authenticity of the medicine can be checked,but the advantages and disadvantages are difficult to distinguish.Therefore,this subject further improves the quality standards of ginseng and red ginseng and studies the quality evaluation of medicinal materials.It provides a reference for the establishment of ginseng,red ginseng quality grade standards and modern medicinal grade evaluation research,and is important for ensuring the healthy and orderly development of the industry.The practical significance.Methods:By collecting ginseng?132 batches?and red ginseng?212 batches?of medicinal materials and decoction pieces from different sources,the contents of the ginseng and red ginseng standard in the supplement of the 2015 edition of the Chinese Pharmacopoeia are based on the literature.Domestic and foreign research results,drafting quality grade standards.Including trait characteristics?size,color?,inspection?moisture,ash,heavy metals and harmful elements,etc.?,identification items?microscopic,thin layer chromatography?,extracts,content determination,characteristic maps,etc.Comprehensive statistical analysis of traits and other effective indicator components data,confirmed by the expert group,select the quantifiable main indicators that can distinguish the differences in the quality of different medicinal materials,and finally determine the evaluation index and weight coefficient,using the weight-division method The indicators are comprehensively evaluated,and the samples are graded according to the score.Results:Judging by the appearance of the sample and the microscopic and thin layer identification methods,the collected samples are all genuine and meet the experimental requirements.The ginseng and red ginseng waters meet the requirements of the pharmacopoeia.The content of ginseng extract is 24.51-61.28%,and the red ginseng is27.86-66.97%.Through data analysis,there are differences between batches;the content determination and characteristic map In the study,eight kinds of ginseng saponins were highly correlated;the size of the medicinal material was correlated with the leaching,ginsenoside Rb1 and its Rb1/Rf peak area values,so each item was classified as an index component.The determination results of heavy metals and harmful elements all meet the limit standard.The residual amount of the five elements in the medicinal materials is low,and there is a small difference between the batches,which has no correlation,so it is not used as a classification index.The weight coefficient is used to comprehensively evaluate the scores of each indicator component.The ginseng and red ginseng are divided into 4 grades,the first grade of ginseng:comprehensive evaluation score is>390;second grade:320390;third grade:250320;fourth grade:180250;fifth grade Product:<180.Red ginseng first-class products:comprehensive evaluation score is>395;second-class products:330-395;third-class products:comprehensive evaluation score is 265-330;fourth-class products:comprehensive evaluation score is 220-265;fifth-class products:<220.Conclusion:Through comprehensive analysis of the trait appearance and intrinsic index component data of a large number of samples,through the expert group research,select the main indicators that can quantify the difference in quality of different medicinal materials,finally determine the evaluation index and weight coefficient,and apply the weight coefficient to each The index component scores are comprehensively evaluated,and the sample grade is evaluated based on the comprehensive evaluation score.Drafting ginseng and red ginseng quality grade standards for the establishment of complete,competitive,industry-recognized ginseng,red ginseng quality grading standards,methodological evaluation and data support,for the safety and market of ginseng,red ginseng and other Chinese medicinal materials The transaction can effectively guarantee and provide strong support,and also promote,guide and demonstrate the establishment of the grade standards of other local medicines in our province.
Keywords/Search Tags:Ginseng, red ginseng, quality standard, weight coefficient, grade evaluation
PDF Full Text Request
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