Analysis Of Clinical Features Related To Bronchiectasis

Purpose:Investigate the distribution of different Reid classifications in the patients with bronchiectasis,analyze the clinical risk factors of patients with different types of diseases,and explore the relationship between each classification and related indicators.Material and method:Cases of Endocrinology of hospitalized patients with bronchiectasis were collected from The Second hospital of Dalian Medicine University from May,2017 to July,2018.According to the HRCT diagnosis report and Reid classification results,the distribution characteristics of different pathological types of the disease were analyzed.The Reid classification was used as the basis for statistical analysis of the patient's classification and gender,age,smoking history,tuberculosis history,body temperature,heart rate,Respiratory rate,blood pressure,blood routine,blood lipids,albumin,glucose,lung CT,immunological examination?IgG,IgA,IgM,IgE?,erythrocyte sedimentation rate,hypersensitivity CRP,procalcitonin?PCT?,hemoptysis,chest tightness,chest pain Correlation of clinical symptoms,current infections,combined with other respiratory diseases,lung function,and sputum culture results.Results:1.180 cases of bronchiectasis were included,including 80 males and 100 females,with an average age of?68.75±10.40?years old.The number of different Reid classifications was 106?58.89%?in the cystic group>columnar group 53 cases?29.44%?>21 cases?11.67%?in the cystic group.2.General information:?1?There was no significant difference in gender between the three classification groups?P>0.05?.The age difference was statistically significant?P<0.05?,and the average age of the cystic group?70.84±9.487?years was significantly higher than the other two.Group?P<0.05?.?2?The mean duration of disease in 180patients was?21.21±13.68?months,and the average length of hospital stay was?9.01±2.95?days.The difference in disease duration between the three groups was statistically significant?P<0.01?,and the course of the cystic group?24.43±14.734?months was significantly longer than the other two groups.There was no significant difference in the number of hospital stays between the three groups?P>0.05?.?3?Among the 180 patients,32 had a history of smoking and 23 had a history of tuberculosis.There was no significant difference between the three groups?P>0.05?.Clinical information:?1?180 eligible patients were admitted to hospital,the average body temperature was?36.58±0.48??the average heart rate was?84.08±15.17?times/min,the average respiratory rate was?21.70±2.67?times/min,and the mean systolic blood pressure was?76.47±10.98?mmHg,the average diastolic blood pressure is?75.45±10.72?mmHg.The respiratory rate of the three groups was statistically significant?P<0.05?,and the average respiratory rate of the cystic group?23.10±2.28?was significantly faster than the other two groups.There was no significant difference in body temperature,heart rate and blood pressure between the three groups?P>0.05?.?2?There were no significant differences in blood routine mean,blood lipids and albumin between the three groups?P>0.05?.The mean glucose?5.90±2.06?mmol/L between the three groups was statistically significant?P<0.05?.The average value of the columnar group?6.50±2.80?mmol/L was significantly higher than the other two groups.?3?There was no significant difference in mean procalcitonin?PCT??0.15±1.21?ug/L,erythrocyte sedimentation rate?25.23±18.37?mm/h,and immunoglobulin?IgG,IgA,IgM,IgE??P>0.05?.the mean high-sensitivity CRP?26.50±47.26?mg/dl between the three groups was statistically significant?P<0.05?,and the average value of hypersensitive CRP in the cystic group?32.79±54.09?mg/dl was obvious.Higher than the other two groups.?4?Of the 180 patients,76?42.2%?had hemoptysis,94?52.2%?had chest tightness,53?29.4%?had chest pain,140?77.8%?had current infection,and 56had respiratory complications.31.1%),there was no statistically significant difference between the three groups except the hemoptysis?P>0.05?.?5?The results of pulmonary CT showed that there were 149?82.8%?patients with affected lobes?2,and 31 patients?17.2%?with affected lobes>2,and there was no significant difference in CT findings between the three groups?P>0.05?.?6?Sixty patients underwent pulmonary function tests.The mean FEV₁%pred was?72.55±19.49?%,and the mean value of FEV₁/FVC was?72.71±14.03?%.The mean difference of FEV₁%pred between the three groups was statistically significant?P<0.05?,in which the average FEV₁%pred of the cystic group?68.57±21.33?was significantly smaller than the other two groups.?7?The results of sputum culture showed that 22cases?22%?were negative and 78 cases?78%?were positive.Among the positive patients,11?50%?were positive for Pseudomonas aeruginosa,6?27.3%?were positive for Klebsiella pneumoniae,and 2?9.1%?were positive.Staphylococci were positive,and 3?13.6%?were positive for E.coli.There was no statistical significance in each component type.Conclusion:1.Most of the patients with bronchiectasis in this hospital are middle-aged and elderly women.Most of the patients have no history of smoking and tuberculosis,and most of them have current infections.Pseudomonas aeruginosa was the main positive result of sputum culture.,and most patients have lung CT showing the number of affected lung?2,Reid The sac-like type is more common in the classification.2.The Reid classification of patients with bronchiectasis is related to age,duration of disease,respiratory rate,glucose,hypersensitive CRP,hemoptysis,FEV₁%pred,and Candida infection.Older age,longer course,faster respiratory rate,higher hypersensitivity CRP,lower FEV₁%pred value,more susceptible to cystic type,cystic bronchiectasis may be more severe.3.Body temperature,heart rate,blood pressure,blood lipids,albumin,blood routine indicators,PCT,erythrocyte sedimentation rate,immunoglobulin and other indicators have no clear relationship with Reid classification,but still be able to respond to the severity of the disease..