| Objective:To summarize the clinical features of bronchiectasis patients with lung function impairment and analyze the risk factors of pulmonary function injured;Method:Clinical data,pulmonary function test and so on were collected in 94 hospitalized bronchiectasis patients which confirmed by CT from January 2014 to May 2016 in the secondary respiratory department of Xinjiang Uygur Autonomous Region People’s hospital,and to summarize and statically analyze;Results:1.Of the 94 patients,there were 48 males and 46 females;Average age was(56.1433.52 ±)years;Average clinical history was(8.24±10.82)years;There were 80 cases(85.1%)of cough,79 cases(84.0%)of sputum,15 cases(16.9%)of hemoptysis,36 cases(38.3%)with dyspnea,8 cases(8.5%)fever,Chest pain in 12 cases(12.8%),fatigue(12.8%);26 cases(27.6%)smoking;BMI was(24.48 ± 4.48)Kg/m2;The patients had no significant gender differences and the main symptoms were cough,sputum production;2.Of the 94 patients,18 strains of pathogens were cultured,including 4 strains of Pseudomonas aeruginosa,3 strains of Acinetobacter baumannii and 3 strains of Klebsiella pneumoniae and so on.Because the culture positive rate is so low that no further analysis is carried out;3.There were no differences in FEV1% pred,FEV1/ FVC,FVC% pred,RV / TLC and DLCO%pred between different BMI groups.4.The types of bronchiectasis were cylindrical,varicose,cystic and mixed type and of the four types the most common was cylindrical(50/94);The FEV1%pred,FEV1/ FVC,FVC%pred,RV/TLC,DLCO%pred had statically significant difference in four types(P<0.05);Cylindrical bronchiectasis seems to had better pulmonary function than cystic and mixed type.5.Pulmonary ventilation dysfunction in varying degrees had statistically significant in the course of disease,CT score,the number of involved lobes(P<0.05),and also differences between normal and abnormal diffusion function(P<0.05);And meanwhile FEV1%pred,FVC%pred,FEV1/FVC and DLCO%pred were all negatively related to history course,the numbers of bronchiestasis segments and pulmonary lobes involved(P<0.05);Age was only negatively correlated with DLCO%;In contrast,BMI,age,age of onset,WBC,ESR had no difference in lung function(P> 0.05).Conclusion:Duration longer,more pulmonary lobes involved and higher CT scores was often happened in the who had more severe damaged lung function;Cylindrical bronchiectasis seems to had better pulmonary function than cystic and mixed type.Different BMI group had no effect on lung function of bronchiectasis. |
