Study On The Correlation Between Urinary Stone Composition And Metabolic Evaluation In Children With Single Center In Xinjiang

Objective:To explore the correlation between stone composition and metabolic evaluation in children with urinary calculi.Methods:Retrospective analysis of 165 cases of pediatric urinary calculi in children with stones and 43 cases of blood biochemistry,24-hour urine analysis results.Results:Among the children in this group,112 males(67.88%)and 53 females(32.12%),the proportion of males was significantly higher than that of females,the ratio was about 2.11:1;141 cases(85.45%)of Uygur and 16 cases of Han nationality(9.69%),8 cases(4.86%)of other ethnic groups,the proportion of Uygur children is significantly higher than that of Han and other ethnic groups,the ratio is about17.62: 2: 1;in all children with stones,stone parts Kidney stones are the most common,accounting for 76.97%;uric acid stones are the most common stone components,accounting for 44.85%;uric acid stones are the most common in the <7-year-old group,accounting for 52.89%,and 7-14 years old.Calcium oxalate stones are the most common in the group,accounting for about 54.54%.According to Pearson correlation analysis,calcium oxalate stones have obvious correlation with urine volume,urinary potassium,urinary calcium,urine sodium,urinary phosphorus,urine PH value,triglyceride and cholesterol metabolism.The correlation coefficient r is-0.208,-0.190,0.617,0.149,0.210,0.121,0.417,0.327,P values were 0.001,0.003,0.001,0.005,0.003,0.001,0.005,0.033,with statistically significant differences;uric acid stones and urine output,There is a significant correlation between the metabolism of urinary potassium,urinary calcium,uric acid and urine PH.The correlation coefficients r are-0.374,-0.133,-0.573,-0.153,-0.244,and the P values are 0.003,0.004,0.001,0.030,0.005,there is a statistically significant difference.Conclusions: In pediatric urinary calculi patients,the most common stone sitesare kidney stones.The most common stone components are uric acid stones,followed by calcium oxalate stones;stones with calcium oxalate stones and low urine output,low urine potassium,There are significant correlations between high urinary calcium,high urinary sodium,high urinary phosphorus,low urine PH value,hypertriglyceridemia,hypercholesterolemia and other metabolic factors;stones with uric acid stones and low urine volume,Metabolic factors such as low urinary potassium,high urinary calcium,hyperuricemia,and low urine PH have significant correlations.