To Evaluate The Efficacy Of Percutaneous Coronary Intervention And Optimal Medical Therapy In The Treatment Of Stable Coronary Artery Disease:A Meta-analysis

Objective:To evaluate the efficacy of percutaneous coronary intervention(PCI)and optimal medical therapy(OMT)in the treatment of stable coronary artery disease(SCAD)by Meta-analysis.Methods:we searched the relevant literature on stable angina pectoris in PubMed,Cochrane Library Control Center,ClinicalTrails.gov,and knowledge network database.The retrieval time was from the building to 2018-8.In accordance with the inclusion criteria and the exclusion criteria,we selected eligible RCT.Meta analysis was performed with Revman 5.3 statistical software.Results: This Meta-analysis included 9studies,including 7 363 patients in PCI group and 3 577 patients in drug treatment group.The Meta-analysis of cardiogenic mortality,revascularization rate,incidence of myocardial infarction,stroke and total events in interventional group and drug treatment group showed that compared with drug treatment group,interventional group could cause coronary heart disease and cardiogenic events.The incidence of death was reduced by33%(RR=0.67,95%CI: 0.55-0.83),which reduced the incidence of total events of coronary heart disease by 24%(RR=0.76,95%CI: 0.63-0.93).There was no difference in the incidence of stroke between drug treatment group and intervention group(RR=1.16,95% CI: 0.78-1.74).There was no difference in the incidence of myocardial infarction between drug treatment group and intervention group(RR=0.91,95% CI: 0.67-1.23).There was no difference in the incidence of revascularization between the two groups(RR=0.71,95% CI : 0.48-1.04).Conclusion: Compared with the drug treatment group,the intervention group can reduce the incidence of cardiogenic death and total events ofcoronary heart disease,while there is no significant difference in the incidence of stroke,revascularization and myocardial infarction between the drug treatment group and the intervention group.