Application Research Of Coronary Angiography Versus FFR For Guiding Percutaneous Coronary Intervention With Coronary Artery Disease Of Critical Coronary Lesions

Object:To evaluate the coronary artery angiography (CAG) combined with fractional flow reserve (FFR) in the clinical application of interventional therapy of coronary lesions.Methods We consecutively enrolled 79 cases patients from April 2012 to March 2013 in our hospital who coronary angiography(CAG) evaluation lesion diameter stenosis rate between 50%-70%, divided into observation group and control group:The observation group of 50 cases (75 lesions) were used for determination of myocardial FFR pressure wire, only if the FFR was 0.80 or less lesions were implanted drug-eluting stent (DES), postoperative FFR≤0.80 were treated with stent balloon. A control group of 29 cases (45 lesions) were underwent coronary conventional drug treatment,4 cases(6lesions) direct intervention, a total of 6 stents implantation. We compared two groups of patients with general baseline data, risk factors and the number of vascular. The rates of major adverse cardiac events (MACE acute myocardial infarction, revascularization) or angina recurrence were record 1 year after discharge.Results We analyzed the observation group and the control group in patients with normal baseline data and the number of lesions no statistical difference, P> 0.05.We compared the observation group and the control group with major adverse cardiovascular events (MACE, including recurrent angina, revascularization and the incidence of acute myocardial infarction) were (2% vs17.2%, respectively,0% vs11.0%, 2.0% vs17.2%) in duiring 1 year and found the significant difference between them, P <0.05.Conclusion CAG conbined with FFR detection was used to guided coronary heart disease, it could reduce the incidence of recurrent angina, revascularization, acute myocardial infarction.