Factors Affecting Treatment Outcomes Of Pulmonary Tuberculosis In Xinjiang Uygur Population

Objective: To analyze the factors affecting treatment outcomes of pulmonary tuberculosis in Xinjiang Uygur Population,providing a theoretical basis for the prevention and treatment of pulmonary tuberculosis in Xinjiang.Methods: Uygur tuberculosis patients in Xinjiang registered in the Tuberculosis Management Information System from July 2014 to June 2015 were selected.General demographic data(age,gender,place of residence,hukou location,occupation)and clinical data(patient source,sputum smear results,type of tuberculosis,type of treatment,treatment outcomes)of the patients were collected retrospectively,and the factors affecting treatment outcomes were analyzed.Results: Of the 24 298 cases registered,29 had a diagnosis change,889 had no reported treatment outcomes,the remaining 23 380 were eventually included in the study.Among the 23 380 cases,1 490(6.4%)had failed treatment,and 564 died(2.4%)from tuberculosis.Multivariate logistic regression analysis showed that age ?60 years[OR=1.550,95%CI(1.386,1.733)],living in rural areas [OR=1.241,95%CI(1.065,1.446)],professional,technical and managerial workers [OR=2.031,95%CI(1.038,3.9740],retirees [OR=2.050,95%CI(1.073,3.915)],referral receivers [OR=1.812,95%CI(1.190,2.758)],follow-up receivers [OR=1.624,95%CI(1.047,2.517)],positive sputum smear results [OR=1.622,95%CI(1.420,1.854)] and retreatment [OR=1.859,95%CI(1.545,2.237)] were risk factors of tuberculosis treatment failure(P<0.05).Age ?60 years[OR=2.462,95%CI(2.038,2.975)],male [OR=1.394,95%CI(1.174,1.656)],living in rural area [OR=1.265,95%CI(1.002,1.598)],positive sputum smear results [OR=2.027,95%CI(1.652,2.486)],retreatment [OR=1.606,95%CI(1.216,2.121)] were risk factors of death due to tuberculosis(P<0.05).Conclusion: Age,place of residence,occupation,patient source,sputum smear results and treatment type are the influencing factors of tuberculosis treatment failure.Age,gender,place of residence,sputum smear results and treatment type are the influencing factors of death due to tuberculosis.In view of this,relevant departments in Xinjiang should take measures to strengthen the prevention andtreatment of tuberculosis in Uygur population,especially the elderly,persons living in rural areas,retirees,tuberculosis referral receivers,tuberculosis follow-up receivers,persons with positive sputum smear results,or those with tuberculosis retreatment.