| Purpose:By collect clinical data and of the patients cured with traditional Chinese medicine and mifepristone or uterine artery embolization combined with curettage.Compare the changes in menstrual flow within 3 months after treatment,endometrial thickness,intrauterine adhesions,secondary infertility and infertility factors,occurrence of pelvic inflammatory disease,and re-implantation of the placenta after pregnancy,Explore the significance of traditional Chinese medicine in the treatment of placenta accreta for the protection of reproductive function and provide a basis for a wide range of clinical applications.Method: Collected 182 cases of cured placenta implants that met the inclusion criteria from January 1,2013 to December 31,2016 in Shandong Provincial Hospital.The patients were divided into observation group and control group.The observation group consisted of 89 patients treated with traditional Chinese medicine Zhupantang,and the control group consisted of 93 patients treated with mifepristone or uterine artery embolization combined with curettage.During the study period,the observation group was detached in 1 case,the control group was detached in 2 cases,the final observation group was 88 cases,and the control group included 91 cases.Results: There was no significant difference in the age and the history of intrauterine surgery between the two groups(P>0.05).The results are:(1)There were 8 cases of menstrual reduction in different degrees in the observation group,and no amenorrhea occurred.In the control group,there were 64 patients with reduced menstrual flow,9 patients had amenorrhea,8 had uterine amenorrhea,and 1 patient had menstrual thinning and developed into amenorrhea.After the rank sum test,the reduction in menstrual flow was statistically significant at P<0.05 for both groups.(2)In the observation group,8 patients with less menstruation underwent B-ultrasound,5 patients had normal intima thickness,and 3 patients had uneven thickness of the intima;In the control group,60 patients with less menstruation underwent B-ultrasound examination,of which 41 patients had too thin inner membrane and 15 patients had uneven endometrium.After testing,P<0.05,the statistical difference was significant.(3)In the observation group,there was no case of intrauterine adhesions.In the control group,44 patients underwent hysteroscopy,and 28 cases had intrauterine adhesions of different degrees.There was a significant difference between the two groups(P<0.05).(4)The observation group had 46 fertility requirements,37 cases of successfu-l pregnancy,and 9 cases of secondary infertility;the control group had 54 cases of fertility requirements,30 cases of successful pregnancy,and 24 cases of secondary infertility,after testing,P<0.05,the statistical difference was significant.(5)In the observation group,there were 9 cases of secondary infertility,6 cases of past menstruation,and ovulation factors infertility,1 case of infertility due to male factors,and 2 cases of immune infertility;In the control group,there were 24 patients with secondary infertility,14 patients with bilateral fallopian tube obstruction,2 patients with thinning menstrual cycles,and 8 patients with too thin endometrial and intrauterine adhesions.After testing,P<0.05,there is a significant difference.(6)Comparing the occurrence of pelvic inflammatory diseases,there were 3 cases of pelvic inflammatory disease in the observation group and 17 cases in the control group.There was a statistically significant difference between the two groups after test(P<0.05).(7)In the observation group,37 patients were re-pregnant,and 6 of them had recurrent placenta accreta;In the control group,there were 30 cases of re-pregnancy,and 12 cases of recurrent placenta accreta occurred.The inci dence of placenta re-implant-ation in the observation group(16.21%)was far less than that in the control group(40.00%).After examination,P<0.05.There are significant statistical differences.Conclusion: Chinese medicine treatment of placenta accreta can avoid uterine mechanical injury,reduce menstrual flow,intrauterine adhesion,fallopian tube obstruction,pelvic inflammatory disease and other complications,educing the chance of uterine cavity infection and re-placement of the placenta and protecting women's reproductive function.It is of great significance and worthy of clinical application. |
PDF Full Text Request