Clinical Analysis Of 188 Female Puberty Ovarian Tumors

Objective:To analyze the clinical characteristic?histology?pathological features?diagnosis and treatment of female puberty ovarian tumors,provide reference and basis for the diagnosis and treatment.Methods:The clinical data and pathologic results were analysed retrospectively in 188 cases of female puberty ovarian cancer patients,which select from Binzhou Medical University Hospital in 2006 January to 2016 December.All cases were supported by postoperative pathologic.Ovarian neoplasms using the 2014 WHO classification standard for pathological classification.The final dates were performed by statistical software SPSS 19.0,counting matenal were analysed with Chi-square test,with a=0.05 for inspection standards,P<0.05 was considered statistially significant.Results:1.Around puberty women ovarian tumor incidence:The incidence of ovarian tumors increased with the years,and the number of cases increased with age.2.The clinical characteristics of adolescent female ovarian tumors:The abdominal pain and pelvic mass was found on body are the main clinical manifestations,because of different degrees of abdominal pain clinic patients accounted for 54.79%,at the same time may be accompanied by nausea and vomiting,abdominal distension,changes in menstrual symptoms;Due to physical examination found that pelvic neoplasm treatment accounted for 16.49%.Other main clinical symptoms include abdominal distention,ammonites and lower abdominal mass,dysmenorrhea,menstruation to be not moved,etc.Except 16 cases in this group of patients with no charge for personal reasons,for physical examination in all 172 cases,respectively,the abdomen-rectal examination,abdominal palpation,receives diagnosis or(and)triad,this group of data after statistical analysis found that the abdomen-rectal examination rate of the lowest,comparing P<0.05,the difference was statistically significant.3.Imaging examination is mainly for the colour to exceed,CT and MRI,the statistical comparison of colour to exceed ovarian tumor detection rate(98.92%)was higher than CT(72.73%)and rate of MRI(88.89%),colour to exceed the highest detection rate,comparing P<0.05,with statistical significance.CT findings of benign and malignant tumor and histological classification in accordance with the postoperative pathological results the coincidence rate of(86.40%)than the accuracy of MRI(44.44%),the two comparative coincidence rate differences statistically significant(P<0.05).In addition to the four exceptions of 188 cases were a tire protein(AFP),carcinoembryonic antigen(CEA),CA19-9,CA125,HCG;human epididymis protein 4(HE4),neurons enolization enzyme(NSE)in a check to seven kinds of tumor markers.After statistical analysis found that the CA125,CEA and AFP positive rate of the highest in the malignant tumor,and the difference is statistically significant(P<0.05).CA19-9 in germ cell tumor of the highest positive rate,HE4 in epithelial tumors had the highest rate of positive and statistically significant differences(P<0.05).4.The Pathological examination of adolescent female ovarian tumors:Postoperative pathologic examination in 188 patients,188 underwent rapid pathologic examination,by comparison,the border sex of ovarian tumor intraoperative rapid postoperative pathological and histological classification of benign versus malignant masses with pathologic consistent rates were the lowest,statistically significant difference(P<0.05).Postoperative pathological results is given priority to with benign,accounted for 93.09%,pathological type is given priority to with germ cell tumors and the tumor lesion,35.11%and 34.04%respectively.Germ cell tumor incidence is higher than before menstruation after menstruation,and epithelial tumors,rope-stromal tumors and the tumor lesion were lower than after menstruation,differences were statistically significant(P<0.05).188 cases of ovarian tumor was 1.4-40 cm in diameter,an average of about 8.837 cm,by comparison,the greater the diameter of ovarian tumor,benign tumor,the smaller the proportion between sex and the greater the proportion of malignant ovarian tumors,the difference was statistically significant(P<0.05).5.The treatment of adolescent female ovarian tumors:188 patients were performed surgical treatment,benign tumor patients,163 underwent ovarian tumor removal surgery,the remaining 12 bilateral adnexectomy.By comparison,benign ovarian tumor pedicle torsion appendix resection rate higher than that of the pedicle torsion,compare the differences between statistically significant(P<0.05).3 patients with border tumors are early,preserving fertility function of conservative surgery.10 cases of malignant tumor patients,8 cases of preserving fertility function,2 underwent comprehensive stage surgery.1 case of border tumor patients,3 cases of malignant tumor patients receiving adjuvant chemotherapy.6.The misdiagnosis of adolescent female ovarian tumors:188 patients in 18 cases of misdiagnosis,the misdiagnosis rate was 9.57%(18/188),the main misdiagnosed as acute gastroenteritis,appendicitis.12 cases of emergency patients,4 cases were misdiagnosed,the misdiagnosis rate was 33.33%(4/12),the main misdiagnosed as acute appendicitis.Conclusions:1.The number of cases of ovarian cancer in adolescent women is increasing year by year and is increasing with age.2.Women puberty ovarian tumor is benign,more pathological type is given priority to with germ cell tumors,so if after diagnosis,should be timely surgical treatment,to prevent acute abdominal disease such as pedicle torsion or tumor rupture,leading to impaired fertility.3.Around puberty women ovarian tumors atypical clinical symptoms are abdominal pain,easy misdiagnosis,diagnosis depend mainly on college physical examination and imaging examination,the preferred colour to exceed examination,when necessary joint CT and MRI,the tumor markers can also auxiliary diagnosis.4.Women puberty ovarian tumor treatment is mainly surgery,if it is a benign tumor,tumor removal surgery,as far as possible if border sex or malignant tumor,in addition to retain reproductive function as much as possible,still need to tumor resection clean,malignant tumor should be in strict accordance with FIGO staging chemotherapy,at the same time can take chemotherapy during ovarian function protective measures,in order to improve the survival quality and pregnancy rate.5.Strengthen to the attention of the female puberty ovarian tumor,strengthen the period of the female patients with pelvic examination,proposes an annual physical examination,early detection,early diagnosis and early treatment.