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The Study Of Efficacy Of Gcsmt In The Patients With Lung Cancer

Posted on:2019-11-01Degree:MasterType:Thesis
Country:ChinaCandidate:A N YanFull Text:PDF
GTID:2404330569999155Subject:Internal Medicine
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Background: There are about 1.6 million newly diagnosed lung cancer patients each year in the world.Lung cancer ranks first in China's cancer deaths,and its morbidity and mortality rate are still increasing year by year.The five-year survival rate of lung cancer does not exceed 15%,which poses a great threat to human health and life.When lung cancer is discovered,it is often already advanced.Physical discomfort,psychological stress,and stress emotions that could lead to a vicious cycle between psychology and physiology in cancer.A large number of studies have shown that mental and psychological factors play an important role in the occurrence,development,and prognosis of malignant tumors.Under the modern bio-psycho-society new medical model,the development of psychological disorders such as emotions and stress and pathophysiology Physical symptoms have a close relationship.Previous clinical studies have found that computer open-minded treatment has a positive impact on the psychological,physical,and social functions of cancer patients such as breast cancer.This has laid a solid foundation for the development of research on the study of efficacy of GCSMT in the patients with lung cancer.Objective: Group Computer Story-version Magnanimous Therapy(GCSMT)was applied to patients with advanced lung cancer,and analyzed in multiple levels from the psychological,subconscious,physical,physiological,and social aspects.The psychological intervention therapy provides evidence for the rehabilitation status of patients with advanced lung cancer in various aspects.Methods:1.Combining the results of previous research,the four treatment methods of computer psychotherapy,group psychotherapy,open-minded relaxation psychotherapy and story psychotherapy are combined to create the Group Computer Story-version Magnanimous Therapy(GCSMT)to form a vivid and rich set of Humanistic colors,simple and convenient psychological treatment methods.2.Eighty patients with advanced lung cancer who met the inclusion criteria and volunteered to participate in the study and signed informed consent form were divided into 40 subjects in the GCSMT group and 40 in the control group according to the matching grouping principle.For the GCSMT group,the Group Computer Story-version Magnanimous Therapy(GCSMT)was given at the same time as conventional clinical anticancer treatment.The duration was 2 weeks,4 times per week,and each intervention time was about 40 minutes,totaling 8 times.For the control group,only clinical routine anticancer treatment was given.80 lung cancer patients were assessed by questionnaire before and 2 weeks after the treatment.The questionnaires were as follows: Psychosomatic Statue Scale for Canner Patients(PSSCP),Tumor Psychological Scale(TPS),Psychological Adjustment Scale for Cancer Patients(PASCP),Cancer Coping Modes Questionnaire(CCMQ),Enterprising and Magnanimous Questionnaire(EMQ),Functional Living Index-Cancer(FLIC),Hospital Anxiety Depression(HAD)and House-Tree-Person Subconscious Painting Test(HTP);Simultaneous assessment of physiological status and immune function in patients with lung cancer The specific conditions for detection of the changes are as follows: brain waves(alpha,beta,theta,SMR),skin,skin temperature,respiration,heart rate,blood pressure,and immunoglobulin(Ig A,Ig M,Ig G)and Natural Killer(NK);and GCSMT treatment of clinical characterization evaluation.Results:1.Complete the Group Computer Story-version Magnanimous Therapy(GCSMT)2.Results of psychological and social functional indicators (1)Evaluation results of the Psychosomatic Statue Scale for Canner Patients(PSSCP): After 2 weeks of psychological intervention in the GCSMT group,lung cancer patients' "psychological" dimension score,"body dimension" dimension score,"social function" dimension score,"psychological malleability dimension score" and "total mean score"(1.77±0.22,1.81±0.29,2.26±0.36,2.70±0.38,2.08±0.15)were all lower than the scores of two weeks ago(1.92±0.26,2.00±0.33,2.51±0.51,3.22±0.57,2.33±0.21).The difference was significant(P<0.01).After 2 weeks of routine clinical anti-cancer treatment,the “psychology” dimension,“body” dimension,“social function” dimension,“psychoplasticity” dimension and “total average score” of the lung cancer patients in the control group(1.94±0.35,2.26±0.31,2.83±0.50,3.18±0.65,and 2.48±0.13)were all higher than the scores 2 weeks ago(1.91±0.33,2.12±0.42,2.66±0.52,3.10±0.69,2.37±0.23).According to statistics,there are significant differences in the dimensions of "somaticity","social function" and total average(P <0.05),and there is no significant difference between "psychiatric" dimension and "psychoplasticity" dimension(P> 0.05).(2)Evaluation results of the Tumor Psychological Scale(TPS): After 2 weeks of psychological intervention in GCSMT group,lung cancer patients' "personality characteristics" dimension scores,"cognitive habits" dimension scores,"emotional performance" dimension scores,"subconscious" dimension scores and "total average points"(1.99±0.20?1.98±0.20?1.84±0.19?1.43±0.19?1.86±0.10)were all lower than the scores 2 weeks ago(2.00±0.17?2.04±0.18?1.89±0.27?1.45±0.17?1.90±0.13),and the differences were not significant(P>0.05).In the control group,after 2 weeks of conventional anti-tumor therapy,the “emotional performance” dimension score,“subconscious” dimension score and “total average score”(1.90±0.21,1.54±0.29,1.92±0.17)of lung cancer patients were higher than two.The scores before 2 weeks(1.87±0.29,1.49±0.27,1.91±0.18)were not significantly different(P>0.05).The scores of “personal characteristics” dimension and “cognitive habit” dimension(1.97±0.22,2.07±0.23)were lower than the scores of two or two weeks ago(2.02±0.26,2.07±0.20),with no significant difference(P>0.05).(3)Evaluation results of the Psychological Adjustment Scale for Cancer Patients(PASCP): After 2 weeks of psychological intervention in the GCSMT group,lung cancer patients scored in the “emotion/self-esteem” dimension,“subjective feelings” dimension, “interpersonal relationship/social life” dimension,“daily life” dimension,and “other” dimensions and the "total average"(3.49 ± 0.32,3.45 ± 0.27,3.00 ± 0.38,3.47 ± 0.30,3.37 ± 0.30,3.42 ± 0.21)were higher than the scores of two weeks ago(3.33 ± 0.19,3.30 ± 0.21,2.79 ± 0.29,3.30±0.28,3.21±0.31,3.16±0.13).The difference was statistically significant(P<0.05).After 2 weeks of conventional anti-tumor therapy in the control group,lung cancer patients' “emotion/self-esteem” dimension score,“subjective feeling” dimension score,“daily life” dimension score,“other” dimension score and “total average score”(3.54±0.33,3.29±0.41,3.41±0.50,3.31±0.43,3.30±0.28)were all higher than the scores before 2 weeks(3.50±0.49,3.26±0.50,3.33±0.61,3.25±0.65,3.26±0.47).The difference was not statistically significant(P>0.05).The “interpersonal/social life” dimension score(2.69±0.43)was lower than the score two weeks ago(2.72±0.56),and the difference was not statistically significant(P>0.05).(4)Evaluation results of the Cancer Coping Modes Questionnaire(CCMQ): After 2 weeks of psychological intervention in the GCSMT group,lung cancer patients' “avoidance and repression” dimension scores,“subversion” dimension score,“fantasy” dimension score,and “vent” dimension score(1.77±0.30,1.79±0.24,1.92±0.44,1.83±0.25)were all lower than the scores 2 weeks ago(1.95±0.30,2.26±0.37,1.95±0.40,1.84±0.34).According to statistics,the difference of the “avoidance and repression” dimension and the "yield" dimension were statistically significant(P<0.05).The scores of "fantasy" dimension and "vent" dimension had no significant difference(P>0.05).The “face” dimension scores and “total average scores”(2.97±0.23,2.13±0.14)were higher than the scores for the two weeks before(2.24±0.30,2.07±0.17).According to statistics,“face” dimension scores were significant(P<0.05),but the “total average scores” was not statistically significant(P>0.05).After 2 weeks of conventional anti-tumor therapy in the control group,the "total average scores" dimension score,"face" dimension score,"yield" dimension score,and "fantasy" dimension score(2.09 ± 0.19,2.50 ± 0.40,2.16±0.32,1.91±0.43)were all higher than the scores 2 weeks ago(2.08±0.19,2.45±0.41,2.15±0.43,1.88±0.42).There was no statistically significant difference(P>0.05).The “avoidance and repression” dimension scores and “vent” dimension score(1.91±0.34,1.76±0.38)were lower than the scores of two weeks ago(1.93±0.37,1.80±0.38),and there was no significant difference(P>0.05). (5)Evaluation results of the Enterprising and Magnanimous Questionnaire(EMQ): In the GCSMT group after 2 weeks of psychological intervention,lung cancer patients' "positive aggressiveness" dimension score,"open-minded tolerance" dimension score and "total average score"(3.04 ± 0.18,3.20 ± 0.19,3.12 ± 0.13)were higher than 2 weeks.The former scores(2.93±0.24,3.13±0.15,3.02±0.14),after statistics,the scores of the “total average score” and “proactive” dimensions are all significant(P<0.05),but “openminded and tolerant” was no significant difference(P>0.05).After 2 weeks of conventional anti-tumor therapy in the control group,the “positive progress” dimension score,“open-mindedness tolerance” dimension score and “total average score”(2.97±0.28,2.96±0.42,2.97±0.27)were all lower than the scores 2 weeks ago(2.99±0.30,3.01±0.41,3.00±0.27),with no significant difference(P>0.05).(6)Evaluation results of the Functional Living Index-Cancer(FLIC): After 2 weeks of psychological intervention in the GCSMT group,lung cancer patients' "good body and ability" dimension score,"psychological well" dimension score,"difficult due to cancer" dimension score,"social good" dimension score,"nausea" dimension score and "total average scores"(4.27 ± 0.72,4.93 ± 0.41,3.28 ± 0.90,4.78 ± 0.73,4.90 ± 0.71,4.42 ± 0.43)were higher than two weeks ago(3.76 ± 0.42,4.50 ± 0.53,2.83±0.45,4.18±0.94,4.48±0.98,3.94±0.39).According to statistics,the dimensions of "good body and ability","psychological well","difficult due to cancer","social good",and "total average scores" were significant(P<0.05),but there was no significant difference in scores of “nausea”(P>0.05).After 2 weeks of conventional anti-tumor therapy in the control group,lung cancer patients had "total average score","difficult due to cancer" dimension,and "nausea" dimension(3.76±0.66,2.61±1.07,4.78±1.50).The scores were higher than 2 weeks ago(3.75±0.86,2.46±0.89,4.43±1.70).According to the statistics,there was no significant difference(P>0.05).The "good body and ability" dimension score,"good psychological" dimension score and “good social” dimension score(3.35±0.82,4.57±0.63,3.86±1.54)were lower than the scores of two weeks ago(3.36±1.12,4.71±0.88,3.94±1.82).After statistics,there were no significant difference in the scores.(P>0.05).(7)Evaluation results of the Hospital Anxiety Depression(HAD): After 2 weeks of psychological intervention in the GCSMT group,lung cancer patients' "total score","anxiety" dimension score,and "depression" dimension score(12.58±2.43,5.08±1.40,7.50±1.43)were lower than 2 weeks ago(15.93±2.12,6.58±1.71,9.35±1.67).After statistics,there were significant difference in the scores(P<0.05).In the control group after 2 weeks of conventional anti-tumor therapy,the scores of “total score”,“anxiety” dimension and “depression” dimension of lung cancer patients(17.43±3.01,6.90±2.13,10.52±2.20)were higher than 2 weeks ago(16.83±3.37,6.75±2.31,10.08±2.15).After statistics,there were no significant difference in the scores.(P>0.05).(8)Evaluation results of the House-Tree-Person Subconscious Painting Test(HTP): The overall picture of lung cancer patients in the GCSMT group before the psychological intervention was monotonous and not full,the layout was lack of completeness,the proportions were inconsistent,the pens were hesitant,the pens dropped badly,the lines were curved and blurred,the stroke pressure was light,the windows were intermittent or Missing;After the psychological intervention,the overall picture of the painting is fuller and more viable than before the intervention.The layout is relatively complete.The proportion is more coordinated than before.The houses,trees and people are more vivid and vivid.The trees are dotted.The green leaves are full of vitality,the house is more complete,the characters' portraits are more vivid and detailed,the lines are complete and clear,the strokes are powerful and smooth,and in addition to the room characters,trees and people,additional objects appear on the screen,such as the sun represents vitality and vitality;people mention buckets and represent love for life and love for life.The active transmission point is more than the negative transmission point.The control group of lung cancer patients can be seen in the conventional anticancer treatment.The difference between the pictures before and after 2 weeks is not significant.The overall picture is monotonous and not full,there is no vitality and vitality,the layout lacks completeness,the proportion is not coordinated,the lines are simple,and the strokes are not smooth.Hesitant and intermittent,with no attachments,the characters are simple to depict,and there are fewer active transmission points.3.The Physiological results(1)The patient's respiration,blood pressure,and heart rate assessment results: After 2 weeks of psychological intervention in the GCSMT group,diastolic blood pressure and respiratory value(73.53±6.56,19.25±0.74)were lower than those of the two weeks ago(75.90±6.38,19.50±0.64),but the statistics showed no significant difference(P>0.05).The systolic blood pressure and heart rate value(118.63±10.96,80.18±5.60)were lower than the value 2 weeks ago(125.18±9.68,82.43±7.37).Statistically,the difference was statistically significant(P<0.05).In the control group after 2 weeks of conventional antitumor therapy,the systolic blood pressure,heart rate,and respiration of lung cancer patients(127.53±14.26,84.58±7.97,19.78±1.35)were higher than those of two weeks ago(125.35±13.25).84.48±7.78,19.55±1.58).Statistically,there was no significant difference(P>0.05).The diastolic pressure value(77.50±9.27)was lower than the value 2 weeks ago(77.98±9.87).After statistics,there was no significant difference(P>0.05).(2)Evaluation of skin potential,skin temperature,and brain wave(?,?,?,and SMR)value of the patient: After 2 weeks of psychological intervention in the GCSMT group,the skin potential,skin temperature,? wave,and ? wave value of lung cancer patients(4.17±0.37,34.24±0.49,12.82±1.06,21.61±2.66)were all lower than the value 2 weeks ago(4.27±0.29,34.30±0.71,13.34±1.06,23.05±1.93).The differences of skin potential,? wave and ? wave value were statistically significant(P<0.05).But there was no significant difference in skin temperature(P>0.05).The value of ? wave and SMR wave(12.70±1.05,8.30±0.80)were higher than those of two weeks ago(12.29±1.63,8.21±0.72).Statistically,the difference of ? wave valuewas statistically significant(P<0.05).However,there was no significant difference in SMR wave value(P>0.05).In the control group,after 2 weeks of conventional anti-tumor therapy,the value of skin potential,skin temperature,? wave,and ? wave(4.37±1.32,35.14±1.08,12.60±5.72,13.12±4.13)were higher in lung cancer patients.The value before 2 weeks(4.33±1.32,35.10±1.06,12.58±5.70,and 12.96±4.15)were not statistically significant(P>0.05).The value of ? wave and SMR wave(23.99±9.91,8.62±2.11)were lower than 2 weeks ago(25.62±11.14,8.65±2.46).Statistically,the difference of ? wave value was statistically significant(P<0.05).However,there was no significant difference in SMR wave value(P>0.05).(3)Evaluation of the three items immunoglobulin(Ig A,Ig G,Ig M)and the natural killer cell(NK): In the GCSMT group after 2 weeks of psychological intervention,the immunoglobulin Ig A,Ig M and natural killer cell NK value of lung cancer patients(2.26±1.42,1.36±1.36,15.64±8.74)were higher than those of the two weeks ago(2.14±0.95,1.23±0.92,14.31±7.52),and the statistics showed no significant differences(P>0.05).The Ig G value(10.78±3.60)was lower than the value 2 weeks ago(11.07±2.84).After statistics,there was no significant difference(P>0.05).In the control group,after 2 weeks of conventional anti-tumor therapy,the Ig A,Ig G,Ig M,and NK value of lung cancer patients(2.57±0.95,11.73±3.54,0.94±0.54,15.06±7.18)were lower than those of two weeks ago(2.58±1.20,12.86±3.49,1.05±0.63,17.96±7.83).According to statistics,the differences of Ig G and NK value were statistically significant(P<0.05)and there were no significant differences between Ig A value and Ig M value(P>0.05).4.Clinical qualitative evaluation: Patients treated with lung cancer in the Group Computer Story-version Magnanimous Therapy(GCSMT)believe that the treatment is based on colorful small stories and real cases to give everyone insight and inspiration.This makes everyone feel broad,mind and body relaxed,can very well understand the essence and true meaning of open-minded.The family members of lung cancer patients believe that the treatment can improve the patient's anxiety,depression,negative emotions,and improve patient compliance.As family members,their psychological pressure is reduced,their mood improves as the patient's mood improves,and they can actively confront the disease with the patient.The medical staff believe that the treatment will enable patients to cooperate more actively with the treatment and improve the medical effect and medical service level.Conclusion: For patients with advanced lung cancer,the Group Computer Storyversion Magnanimous Therapy(GCSMT)has positive effect on emotional,physical,psychological,social,and physical aspects.It can help patients achieve a state of mind and relaxation.It helps to alleviate the psychological negative emotions such as anxiety,depression,fear,inferiority,and appetite,sleep,and pain in patients with lung cancer;It can improve their social function,psychological behavioral plasticity and psychological adjustment ability;It can enhance their positive,optimistic psychological attitudes and beliefs.It allows them to face disease and treatment with a more positive and optimistic attitude,and improve their compliance with clinical treatment.At the same time,it also helps to improve the state of their immune function and physiological function and improve the quality of life of lung cancer patients.
Keywords/Search Tags:Group computer story open-minded treatment, Lung cancer patients, Rehabilitation, Efficacy
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