Correlative Study On TCM Syndromes Of Coronary Heart Disease And Cardiopulmonary Exercise Test Indexes

Objective:The purpose of this study is to investigate the correlation between TCM syndrome type and cardiopulmonary exercise test index of coronary heart disease,and Provide a reference for TCM syndrome differentiation of coronary heart disease.Methods:A total of 162 patients with coronary heart disease with unstable angina treated at the First Affiliated Hospital of Henan University of Traditional Chinese Medicine from January 2017 to December 2017 were collected.According to the TCM symptom evaluation form of patients,they were dialectically typed.Another 20 medical examiners were selected as controls for the non-CHD group.Record general patient data and perform cardiopulmonary exercise testing on all enrolled patients.The use of statistical software to analyze the correlation between cardiopulmonary exercise test indicators and TCM syndrome types of coronary heart disease provides a reference for TCM syndrome differentiation of coronary heart disease.Results:1.A total of 155 patients who completed the trial for unstable angina of coronary heart disease,the syndrome distribution of 42 cases of heart-blood stasis syndrome,phlegm stagnation cardiopathy syndrome in 37 cases,qi deficiency and blood stasis syndrome in 26cases,24 cases of qi-yin deficiency syndrome,18 cases of qi stagnation cardiopulmonary syndrome,there were a total of 8 cases of cold condensation heart pulse and yang of Xinshen deficiency.The distribution of age,height,weight,etc.was consistent among the groups,with no significant difference（P>0.05）.2.The Peak VO2 levels of different syndromes of coronary heart disease were not significantly different from those of non-coronary heart disease,but the heart-blood stasis syndrome proved to be higher than the deficiency of qi-yin deficiency syndrome.The percentage of Peak VO2 accounts for its predicted value in the coronary heart disease syndrome group was significantly lower than the non-coronary heart disease group,and the qi stagnation cardiothoracic group was significantly higher than the qi and yin deficiency group,the difference was statistically significant（P<0.05）.The level of VO2@AT in different syndromes of coronary heart disease is not different from those in non-CHD group,but the evidence of heart-blood stasis syndrome and phlegm stagnation cardiopathy syndrome is significantly higher than that of qi stagnation cardiopulmonary syndrome.The difference was statistically significant（P<0.05）.The level of VO2/Kg@AT in coronary heart disease with qi deficiency and blood stasis syndrome,qi-yin deficiency syndrome,and qi stagnation cardiopulmonary syndrome are significantly lower than those in non-CHD group,while the level of heart-blood stasis syndrome and phlegm stagnation cardiopathy syndrome are significantly higher than those of qi-yin deficiency syndrome and qi stagnation cardiopulmonary syndrome.The Peak Mets,and Mets@AT indicators in phlegm stagnation cardiopathy syndrome,qi deficiency and blood stasis syndrome,qi-yin deficiency syndrome,and qi stagnation cardiopulmonary syndrome of the coronary heart disease group were significantly lower than those in the non-coronary heart disease group;Comparion of each group,Peak Mets level of qi deficiency and blood stasis syndrome and qi-yin deficiency syndrome,Mets@AT level of qi-yin deficiency syndrome were significantly lower than the heart-blood stasis syndrome,the difference was statistically significant（P<0.05）.The level of O2 pulse in each group of coronary heart disease is significantly lower than that in non-coronary heart disease group;and the O₂ pulse level of phlegm stagnation cardiopathy syndrome is significantly higher than that of qi deficiency and blood stasis syndrome,qi-yin deficiency syndrome and qi stagnation cardiopulmonary syndrome.The level in heart-blood stasis syndrome is significantly higher than qi-yin deficiency syndrome and qi stagnation cardiopulmonary syndrome.The level in qi deficiency and blood stasis syndrome is proved to be significantly higher than the qi-yin deficiency syndrome,the difference is statistically significant（P<0.05）.The level of VE/VO2@AT in patients with coronary heart disease in phlegm stagnation cardiopathy syndrome,qi deficiency and blood stasis syndromeand qi-yin deficiency syndrome were higher than those in non-CHD group（P<0.05）.The levels of VE/VCO2@AT in patients with phlegm stagnation cardiopathy syndrome,qi deficiency and blood stasis syndrome,and qi-yin deficiency syndrome of coronary heart disease group are significantly higher than those in non-coronary heart disease group（P<0.05）.3.Heart-blood stasis syndrome of coronary heart disease unstable angina is negatively correlated with the percentage of Peak VO₂ accounts for its predicted value and positively correlated with Peak Mets;phlegm stagnation cardiopathy syndrome is positively correlated with O2 pulse;qi deficiency and blood stasis syndrome is negative correlation with Peak VO2 and positive correlation with VO2@AT;qi-yin deficiency syndrome is negatively correlated with O2 pulse;qi stagnation cardiopulmonary syndrome is positively correlated with the percentage of Peak VO₂ accounts for its predicted value and negatively correlated with VO2@AT.Conclusion:1.The common types of coronary heart disease patients with unstable angina are heart-blood stasis syndrome,phlegm stagnation cardiopathy syndrome,qi deficiency and blood stasis syndrome,qi-yin deficiency syndrome,and qi stagnation cardiopulmonary syndrome.2.The Peak VO₂%pred、Peak Mets、Mets@AT and O₂ pulse indicators of cardiopulmonary exercise test can provide reference for syndrome differentiation of coronary heart disease with unstable angina.3.The smaller the percentage of Peak VO₂ accounts for its predicted value in patients with coronary heart disease is,the larger the Peak Mets is,the more likely it is to identify the heart and blood stasis syndrome.The greater the O₂ pulse value,the more likely it is to identify the phlegm stagnation cardiopathy syndrome.The smaller Peak VO2 value in patients with heart disease,the greater the VO₂@AT value,the more likely to be syndrome of qi deficiency and blood stasis.The smaller the O₂ pulse value in patients with coronary heart disease,the more likely to be syndrome of qi and yin deficiency.The larger the percentage of Peak VO₂ accounts for its predicted value in patients with coronary heart disease is,the smaller the VO₂@AT value is,and the more likely it is to differentiate into a qi stagnation cardiogram.So,Cardiopulmonary exercise test indicators correlate with TCM syndromes of coronary heart disease with unstable angina.