Comparative Study On The Level Of Lipoprotein-Associated Phospholipase A2 Between Different TCM Types Patients With Coronary Heart Disease After Percutaneous Coronary Intervention

ObjectiveUnderstand the differences in the level of Lp-PLA2 between three TCM syndrome type(phlegm turbidity syndrome,blood stasis syndrome and qi deficiency syndrome)patients with CHD after PCI by test their owm Lp-PLA2 levels,explore the higher level of Lp-PLA2 is in which type of syndrome in CHD patients after PCI,analyze the severity of coronary lesions between the coronary heart disease patients in different TCM syndrome types,and predict the possibility of recurrent coronary artery stenosis in different CHD patients after PCI.Methods75 cases of the coronary heart disease patients who have an operation of PCI as research group in department of cardiovascular medicine were collected from April 2016 to December 2016 in Guangdong Provincial Hospital of integrated Traditional Chinese and Western medicine.75 patients were divided into phlegm turbidity syndrome,blood stasis syndrome and qi deficiency syndrome according to TCM syndrome Different standards,compared with the control group,25 cases(between 40 and 90 years old,male or female)of healthy persons were collected in the same period.Fasting the Eligible control group crowd' s blood after they are hospitalized on an empty stomach,the researched group crowd is fast blood in day 1 and 4 days after PCI,and the level of Lp-PLA2 is tested between the two groups all by immune enhancement turbidimetric method.Compare the level of Lp-PLA2 between research group and the healthy controls,compare the level of Lp-PLA2 between different TCM syndrome type patients with coronary heart disease in day 1 and 4 days after PCI,and aslo compare the level of Lp-PLA2 in different periods between the three groups of western medicine type patients with coronary heart disease after doing the percutaneous coronary intervention.Analysis the results of research by SPSS 19.0.Results1.The level of Lp-PLA2 in the patients with coronary heart disease in day 1 and 4 days after PCI were higher than that in the healthy control group,the difference was statistically significant(P<0.05).2.The level of Lp-PLA2 between the three different groups of TCM syndrome type patients with coronary heart disease in day 1 after PCI surgery are not equal,by comparison,the level of Lp-PLA2 from high to low isphlegm turbidity syndrome>blood stasis syndrome>qi deficiency syndrome.3.The level of Lp-PLA2 between the three different groups of TCM syndrome type patients with coronary heart disease in day 4 after PCI surgery are not equal,by comparison,the level of Lp-PLA2 from high to low isphlegm turbidity syndrome>blood stasis syndrome>qi deficiency syndrome.4.The level of Lp-PLA2 between the three groups of western medicine type patients with coronary heart disease in day 1 after PCI are not equaL,after a statistical comparison,the level of Lp-PLA2 from high to low is AMI>UAP>SAP.5.The level of Lp-PLA2 between the three groups of western medicine type patients with coronary heart disease in day 4 after are diverse from each other,after a statistical comparison,the arrangement of the Lp-PLA2 level from high to low is AMI>UAP>SAP.ConclusionLp-PLA2 as a strong blood vessels proinflammatory factor can evaluat the activity of coronary heart disease,aslo it can be used as the judgment of the probability index in coronary artery restenosis about different western medicine types patients with coronary heart disease after PCI.The level of Lp-PLA2 between the different types of TCM syndrome patients with coronary heart disease after PCI is obvious different,which can provide a objective basis for the TCM syndrome differentiation of coronary heart disease and give a guide to the clinical medicine of traditional Chinese medicine of coronary heart disease,beyond that,it aslo can be used as a objective indicator to judge the size of the restenosis possibility about the kind of TCM syndrome type patients with coronary heart disease patients after PCI.