Literature Review And Clinical Application Of Yang-Warming And Blood-Stasis-Removing Therapy In The Treatment Of Medium And Advanced Ovarian Carcinoma

Objective:Professor Lin Lizhu,a famous traditional Chinese medicine doctor in Guangdong province,has researched on cancer clinical for more than 30 years.She is expert in the treatment of medium and advanced stage of malignant tumor with combination of western medicine and TCM.Professor Lin has accumulated wealth of valuable clinical experience when she is studying and developing TCM oncology.It is of important academic and social value to summarize her clinical experience.This paper intends to summarize professor Lin?s clinical experience in medium and advanced stage of ovarian carcinoma with Yang-warming and blood-stasis-removing therapy,and to analyze her clinical cases about using Yang-warming and blood-stasis-removing therapy to cure medium and advanced stage of ovarian carcinoma.Methods:1.Literature arrangement: organize and analyze the content in ancient and modern literature about ovarian carcinoma;summarize the ancient and modern doctor?s recognition of ovarian carcinoma;sort and sum up the content in ancient and modern literature about treating ovarian carcinoma with Yang-warming and blood-stasis-removing therapy;confirm that Yang-warming and blood-stasis-removing therapy has theoratical,ractical and scientifical basis in treating medium and advanced stage of ovarian carcinoma.2.Selection and analysis of clinical cases: summarize professor Lin?s academic thinking of using Yang-warming and blood-stasis-removing therapy to treat medium and advanced stage of ovarian carcinoma;collect and discuss the relative typical clinical cases,which help confirm that Yang-warming andblood-stasis-removing therapy has clinical meaning in treating medium and advanced stage of ovarian carcinoma.Results:1.The knowledge about Yang-warming and blood-stasis-removing therapy to treat ovarian cancer by the medical practitioners is inherited and developing,and the rich clinical experience and academic thinking of doctors are worthy for studying deeply.2.The 10 typical cases from Professor Lin were collected: 3 patients were in ? stage,4 patients were in ? period,3 patients were in stage ?.All the 10 patients were subjected with operation or chemotherapy.5 patients had no relapse after initial treatment,and 2 patients of whom used purely TCM treatment for 32 months and 31 months respectively.Other patients used combination treatment of TCM and chemotherapy,and the longest time was 33 months and the shortest was 12 months.Another 5 patients were suffered from recurrence: 2 were treated with purely TCM for 43 months and 37 months;the other 3 patients were treated with TCM and chemotherapy,and the longest time was 33 months and shortest was 6 months.Conclusion:1.The formation,development and effects of treatment of malignant tumor are closely related to �Yang deficiency and blood stasis�.The treatment should be based on accurate differentiation and centered on Yang-warming and blood-stasis-removing therapy.A number of modern pharmacological and clinical researches confirm the treatment of medium and advanced stage of ovarian carcinoma with Yang-warming and blood-stasis-removing therapy.Also,some Chinese patent drugs has been validated by CFDA for ovarian carcinoma caused by �Yang deficiency and blood stasis�.Researches on the treatment of using began from pre-Qin Dynasty.However,there is still a few deep and comprehensive researches.2.From professor Lin?s prospective,most medium and advanced stage of ovarian carcinoma had the syndrome of �Yang deficiency and blood stasis�.The "Yang-warming and blood-stasis-removing therapy" she used to cure medium and advanced stage of ovarian carcinoma had 7 characteristics:(1)using Treatise on Febrile and Miscellaneous Diseases and classical prescription toguide the treatment;(2)using medicine suits;(3)"Tonifying fire source to the yuanyang of the right kidney" and "yangqi develops constantly with the help of yinqi";(4)some yang-warming herbs and blood-stasis-removing herbs are used commonly,like Duzhong 15 g,Niuxi 15 g,Bajitian 15 g,Yinyanghuo 15 g,Fuzi 10 g,Ganjiang 10 g,Wuzhuyu 6g,Xiaohuixiang 10 g,Rougui 10 g,Guizhi 15 g,Danggui 10 g,Jixueteng 30 g,Chuanxiong 10 g,Tubiechong 6g,Taoren 10 g,Chishao15g,Eshu 15 g,Hongjingtian 12g;(5)some formulas are commonly used:Sini decoction,Lizhong decoction,Zhenwu decoction,Guizhi fuling decoction,Shenqi boluses,Shaofuzhuyu decoction,Wenjing decoction,Nuanganjian,Dahuang zhechong boluses,Xiayuxue decoction;(6)combination of medicine and food(7)combination of oral and external use.3.The treatment of Yang-warming and blood-stasis-removing with medium and advanced stage of ovarian carcinoma had favorable clinical effects...