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Therapeutic Effects Of Exercise Therapy,Paroxetine And Two Treatments On Anxiety Disorder

Posted on:2019-05-24Degree:MasterType:Thesis
Country:ChinaCandidate:J J XiaoFull Text:PDF
GTID:2404330548491778Subject:Mental Illness and Mental Health
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Objective:To explore the efficacy of exercise therapy,paroxetine and combination of the two treatments in the treatment of anxiety disorders and to improve the quality of health-related quality of life,to further explore the role of exercise therapy in anxiety disorders,and to provide some support for the clinical treatment of anxiety disorders.Method:Patients with anxiety disorders who were diagnosed at the psychological clinics of a tertiary care hospital from April1,2017 to January 29,2018 were collected.A total of 89 cases were collected,including 28 in the exercise therapy group,30 in the paroxetine group,and 31 in the exercise therapy and paroxetine group.When the three groups of patients were enrolled in the group,their age,sex ratio,etc.were statistically processed,and the difference was not statistically significant.Record the indicators of exercise cardiopulmonary exercise in exercise therapy group and combination therapy group.To evaluate the efficacy of HAMA and HRSD before and after treatment in the three groups of Patients,and to evaluate the efficacy at the time of treatment and at the 2nd,4th,6th and 8th weeks of treatment(based on the results of the BAI and BDI scales).SF-36 scale was used to assess the quality of life of the three groups before and after treatment.Results:1.Indices of forced vital capacity(FVC),slow vital capacity(SVC),maximum ventilation(MVV)per minute,and indexes for evaluation ofWEBER VO2 motor function classification in exercise therapy group and combination therapy group: maximal oxygen uptake(VO2max)and anaerobic threshold(AT)showed no significant abnormalities in cardiopulmonary function between the two groups,and there was no significant difference between the two groups(P>0.05).2.There was no significant difference in the HAMA scores between the three groups before treatment(F=0.22,P=0.97).The differences between the three groups before and after treatment were statistically significant(F=10.36,P=0.01).There was a statistical difference between the therapy group and the paroxetine group(P=0.03),there was a statistical difference between the exercise therapy group and the combination therapy group(P=0.04),and there was a statistical difference between the paroxetine group and the combination therapy group(P = 0.04).There was no significant difference in HRSD scores between the three groups before treatment(F=0.20,P=0.81).The difference in HRSD scores between the three groups before and after treatment was statistically significant(F=3.43,P=0.04).There was a statistical difference between the group and the paroxetine group(P=0.04),there was a statistical difference between the exercise therapy group and the combination therapy group(P=0.02),and there was no statistical difference between the paroxetine group and the combination therapy group(P= 0.51).3.The BAI and BDI scores of all patients decreased significantly.In the early treatment period(the first 4 weeks),the exercise therapy group andcombination therapy group had faster score reduction than the paroxetine group.It can be considered that exercise therapy combined with paroxetine group may give priority to anxiety effect.4.The score of SF-36 scale increased significantly before and after treatment,and self-assessment of patients' quality of life improved compared with before.However,no significant difference was found between the two groups(P>0.05).The health-related life of the patients in the combined treatment group cannot be considered The quality improvement is better than that of the paroxetine group.Conclusion:1.The combination of single exercise therapy,paroxetine,and two treatment methods for the treatment of anxiety disorders has significant effects,and can significantly improve the anxiety symptoms of patients and improve the quality of life of patients.2.Exercise therapy has obvious effects on the treatment of anxiety disorders,but it is still inferior to the efficacy of paroxetine.The combination of exercise therapy and paroxetine in the treatment of anxiety disorders is significantly better than the exercise therapy group and paroxetine group,which may be exercise therapy for paroxetine has a synergistic effect;in the early stages of treatment,exercise therapy demonstrated superior efficacy compared to oral paroxetine,giving priority to improving the effects of anxiety.3.Exercise therapy can be combined with antidepressant drugs to assist inthe treatment of anxiety disorders.
Keywords/Search Tags:Exercise Therapy, Cardiopulmonary Exercise Testing, Paroxetine, Anxiety Disorder
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