Study On The Relationship Between Insomnia And TCM Constitution In Chronic Non-atrophic Gastritis

Objective:1.Study the correlation between insomnia and TCM constitution in Chronic non-atrophic gastritis patients.2.The etiology and pathogenesis of Chronic non-atrophic gastritis with insomnia are discussed on the basis of the theory of TCM constitution of traditional Chinese medicine.Methods:1.Questionnaire: questionnaire formulated Pittsburgh sleep quality index scale(PSQI)(Appendix 2),Chinese constitution classification and decision scale(Appendix 3)and gastrointestinal symptoms questionnaire(GIS)(Appendix 4).on the other hand,the above scale is made into an electronic questionnaire on the Tencent questionnaire.2.We collected clinical data of the patients who diagnosed Chronic non-atrophic gastritis in the outpatient department,inpatient department and endoscope room of the First Affiliated Hospital of Guangzhou University of Chinese Medicine by questionnaire from May 2017 to February 2018.3.We studied the general condition,PSQI,GIS and TCM constitution distribution of patients with Chronic non-atrophic gastritis,and analyzed the difference of TCM constitution distribution between Insomnia group and non-insomnia group.Results:1.There was no significant difference in gender composition between chronic insomnia group and non-insomnia group,however,there was a statistically significant difference in the age stratification ratio(P<0.05).2.The proportion of patients with chronic non-atrophic gastritis in different genders in PSQI components indicated that only in the case of using hypnotic drugs,the scores were 0.20 ± 0.64 for females and 0.03 ± 0.18 for males,suggesting statistically significant differences(P <0.05);There were statistically significant differences in sleep quality,sleep disturbance,and daytime dysfunction in the PSQI of patients with different constitution.There was no statistical difference in other components.3.The sleep time and hypnotic use of female in insomnia group were 1.48 ± 0.98 and 0.31 ± 0.79 respectively;those of male were 1.36 ± 0.74 and 0.06 ± 0.23,there was a significant difference(P <0.05).There was no significant difference in the total score of PSQI among different constitutional patients,but there was a significant difference in sleep efficiency between sleep disorders(P <0.05).4.There was no significant difference in gastrointestinal symptom scores between patients of different genders and constitutions,but not in patients of different ages.There was no significant difference in GIS between insomnia group and non-insomnia group.5.282 cases of chronic non-atrophic gastritis,qi-depression type up to 63(22.3%)cases,the minimum of only 5(1.8%)cases of special inherited type;different genders,different age groups in patients with no significant difference in TCM consitution distribution.There were significant differences in the TCM consitution distribution among insomnia patients and non-insomnia patients(P <0.05).There were 42 cases of qi-depression type in insomnia group and 21 cases in non-insomnia group(P <0.05).Conclusions:1.Chronic non-atrophic gastritis occurs predominantly in female patients with a male to female ratio of 0.54:1;young and middle-aged patients are predominant,and patients in the middle-aged and older groups are more prone to insomnia.2.The insomnia in patients with chronic non-atrophic gastritis varies in different genders,and women in the insomnia group generally have less sleep time than men and have a high frequency of sleep disturbances,prompting women to take sleeping pills more often than men.The sleep efficiency of the patients of blood-stasis type in the patients with insomnia group is worse than that of other physique,and the patients of qi-depression are most likely to have sleep disorders.3.There was no difference in GIS between male and female patients.GIS in female patients were slightly higher than those in male patients.There was significant difference in GIS among different age groups.The severity of gastrointestinal symptom scores was middle-aged group> older group> young group.In the study,the GIS of the insomnia group was higher than that in the non-insomnia group,but there was no statistical difference.There was no statistical difference in the GIS of the patients with different TCM consitution.4.Chronic non-atrophic gastritis patients physical distribution of TCM with gender and age stratification no significant differences related to distribution in different sleep situation,and between the two groups of biased constitution have different distribution,including qi-depression type insomnia group than the normal group,the damp heat,phlegm dampness patients are more,so the treatment Chronic non-atrophic gastritis patients with insomnia should be " Dispersing Stagnated Liver Qi and Strengthening Spleen ".