The Study Of Clinical Observation Of Tonglin Guben Decoction In Preventing And Treating Ureteral Stent Symptoms

ObjectiveUnderstand the general development rules of ureteral stent Symptoms of ureteral stents indwelling patient.Evaluate Tonglin Guben decoction in preventing and treating ureteral stent Symptoms of the patients who with ureteral stents after the surgery of urinary stones.MethodsA prospective randomized controlled study was carried out in Urology Department of Guangdong Provincial TCM Hospital from 2017.2 to 2018.3.A total of100 patients who indwell ureteral stents after the surgery of urinary stones were randomly assigned to the experimental group and the blank control group(50 cases).On the first day after the retention of ureteral stents,the experimental group began to take the formula of Tonglin Guben decoction once a day and behavioral guidance therapy,and the blank control group was treated with only behavioral guidance.The treatment period was 2 weeks and the observation period was 4 weeks.By comparing the changes in the scores of the blank control group,the general development rules of ureteral stent Symptoms in the patients with ureteral stent were studied.Observed two groups of patients with postoperative on the first day,around the second week,the fourth weeks USSQ score and quality of life index score,compared two groups of patients each time,to evaluate Tonglin Guben decoction in preventing and treating ureteral stent Symptoms of the patients who with ureteral stents.SPSS software 18.0 was used to set up the database,t-test,repeated measurement variance analysis,and the?~2 test were used to carry out statistics.Results1.In general information,it was no significant difference between the two groups in the age,neither nor sex composition(both P>0.05).The two groups were comparable.2.Paired sample t test showed the results of the first day of the blank control group patients USSQ score of lower urinary tract symptoms,body pain,general situation,and the quality of life index score were the highest,the scores of the second week were lower than those on the first day,the difference had statistical significance(P<0.05).The score of work ability and sexual satisfaction in the second week were higher than the first day,differences were statistically significant(P<0.05).Compared with all the scores in the second week and the fourth week,the differences were not statistically significant(P>0.05).3.Paired sample t test showed the results of experimental group patients USSQ score on the first day of the lower urinary were the highest,the scores of the second week were lower than those on the first day,the difference had statistical significance(P<0.05).The score of the body pain and quality of life index score were lowest in the second week,the difference was statistically significant(P<0.05).Experimental group patients USSQ score on the second week of the general situation were lower than those on the first day,the difference had statistical significance(P<0.05),but the differences were not statistically significant(P>0.05)in the second week and the fourth week.Experimental group patients USSQ score on the second week of the work ability and quality of life index scorewere higher than those on the first day,the difference had statistical significance(P<0.05),but the differences were not statistically significant(P>0.05)in the second week and the fourth week.4.Repeated measurement analysis of variance and multivariate analysis of variance were performed on the scores of both groups before and after treatment.The results showed that:The analysis of variance of multiple time points repeated measurement of all items in both groups showed that time had an effect on the change of score in both groups(P<0.05).There was no significant difference in USSQ and quality of life index scores between the two groups on the first day(P>0.05).At the second week,the scores of lower urinary tract symptoms,body pain and quality of life index in the experimental group were significantly lower than those in the blank control group(P<0.05).However,there was no significant difference in scores of sexual satisfaction,work ability and general situation between the two groups(P>0.05).At the fourth week,the scores of lower urinary tract symptoms and body pain in the experimental group were lower than those in the blank control group(P<0.05),however there was no significant difference in the sexual life satisfaction score,work ability,general condition and quality of life index score between the two groups(P>0.05).5.Two subjects in the treatment process had not happened the adverse effect,such as local skin allergies,gastrointestinal reactions,dizziness and so on.ConclusionThe ureteral stent Symptoms was most obvious in the first day postoperative,the reduced in the second week perhaps due to the behavioral guidance therapy work and their own tolerance.As a result of both work ability and sexual satisfaction scores on the first day tended to reflect the situation in front of the surgery,so the score was significantly lower on the first day than in the second week and the fourth week.Eliminate the behavior therapy and its tolerance on the influence of the score,taken the formula of Tonglin Guben decoction once a day can improve the lower urinary tract symptoms,body pain and quality of life index score in patients who with ureteral stent.But there was no significant impact on the general situation and the work ability and sexual satisfaction score.After 2 weeks of drug withdrawal,the efficacy of Tonglin Guben decoction will decrease,and the symptoms of ureteral stenting will rebound again.