Clinical Study On The Four Seasons Intervention Of Susceptible Population Of Cold

ObjectiveIn this study,we conducted a comprehensive intervention of traditional Chinese medicine for four seasons in susceptible people and adopted different fixed traditional Chinese medicine comprehensive intervention programs to intervene in susceptible people with cold.Through evidence-based medical evaluation methods,observe the target program for the target population flu and health status of the intervention effect and program safety.MethodsThe study used uncontrolled treatment,self comparison and case series research method,and the eligible subjects were included in the study.Recruiting 137 cases,adopt the comprehensive intervention technical solution of Chinese medicine intervention group,each season in fixed time using different intervention plans to intervene,intervene in the four seasons in a row,with 1 year.There were 5 points at the end of each season and before intervention,and the subjects' cold and health status were evaluated and compared with those before intervention.ResultsA total of 137 people were included in this study,124 of whom completed the study,and the shedding rate was 9.49%,which was satisfactory.The subjects were mainly middle-aged and elderly,with a large number of females and a high degree of culture.1.The number of colds and the situation of colds: after the four seasons intervention in 1 natural year,the number of colds decreased,the difference was statistically significant(P<0.01),the severity of colds decreased,the difference was statistically significant(P<0.01),the longest days of colds in 1 natural years decreased,the difference was statistically significant(P<0.01),and the total colds decreased significantly.The situation is better than that before intervention.It shows that four seasons intervention can reduce the number of colds in people who are susceptible to colds and relieve the symptoms of a cold.2.Health level: Four seasons intervention could reduce diastolic blood pressure and increase body weight,P<0.01 before and after intervention,,the difference was statistically significant.There was no significant difference in health degree,body temperature,systolic blood pressure and heart rate before and after intervention(P> 0.05),which indicated that the influence of four seasons intervention on the health degree,body temperature,systolic blood pressure and heart rate of people susceptible to colds was not obvious.3.The constitution of TCM and correlation: in the subjects,the two groups,Qi deficiency and Yang deficiency,accounted for a large proportion(70.16%),and the intervention of the four seasons had a certain effect on the bias of Qi deficiency and Yang deficiency,the difference was statistically significant(P<0.01);in the past 1 years the number of colds,Qi and Yang deficiency decreased than non-Qi and Yang deficiency in the case of cold,the difference was statistically significant(P<0.05);In terms of the severity of the cold,there was no significant difference between Qi and Yang deficiency and non-Qi and Yang deficiency,the difference was not statistically significant.(P>0.05).4.Safety: the laboratory indexes(ECG,blood and urine routine,liver function(ALT,AST),kidney function(Cr ? BUN)),before and after intervention,the difference was not statistically significant.(P>0.05),which indicated that the intervention of four seasons had no influence on laboratory indexes of susceptible to colds,but it would cause some adverse events,and the severity of adverse events most the lighter.ConclusionThe four seasons intervention is safe and effective for the people who are susceptible to colds to improve the situation of the susceptible colds.Through the four seasons intervention,the number of colds in the common cold population was decreased,the severity of the cold was reduced,the effect of Qi deficiency and Yang deficiency was more remarkable,and the bias of Qi deficiency and Yang deficiency also had certain conditioning effect.The results showed that the four seasons intervention was of great significance in reducing the frequency of common cold and reducing the severity of cold in susceptible people.It proves that the comprehensive intervention of traditional Chinese medicine in the four seasons can improve the condition of susceptibility to cold,and is a suitable and practical method for TCM.