The Clinical Research Of Treatment ASAH Acute Headache With Xuefuzhuyu Decoction And Shouqingsan Acupoint Sticking

ObjectiveIn this study,the patients with intracranial aneurysmal subarachnoid hemorrhage were used as the research object.With the application of Xuefuzhuyu decoction and Shouqingsan acupoint sticking,the improvement of headache symptoms and the number of erythrocytes in cerebrospinal fluid were observed to evaluete its clinical effect of intracranial aneurysmal subarachnoid hemorrhage headache.MethodsAccording to the inclusion and exclusion criteria,40 patients with aneurysmal subarachnoid hemorrhage hospitalized in craniocerebral ward of the First Affiliated Hospital of Guangzhou University of Chinese Medicine from October 2015 to February 2018 were randomly divided into control group of 20 cases and experimental group of 20 cases.The control group was given Western interventional embolization and conventional treatment of drugs,the experimental group was given Xuefuzhuyu decoction oral and ShouQingSan acupuncture sticking on the base of the treatment of the control group.By observing and comparing the degree of headache,the time of headache relief,the changes of cerebrospinal fluid erythrocyte,TCM syndrome score,Glasgow prognosis(GOS)scores in two groups to verify that the treatment of aSAH acute headache with Xuefuzhuyu decoction and ShouQingSan acupoint sticking is effectived and to explore its mechanism of action.Result1?After 2 weeks of treatment,the effective rate was 90.5% in the experimental group and 90% in the control group.The difference was statistically significant(P<0.05),and theexperimental group was more effective than the control group.2?The VAS scores of the two groups decreased significantly on the 3th day,the 5th day,the 7th day,the 10 th day and the 14 th day after the admission(P <0.05).This shows that both groups of patients after treatment of headache symptoms were improved.And there was significant difference between the two groups in the VAS scores on the 5th,7th and 10 th days after admission.The improvement of the VAS score in the experimental group was better than that of the control group.3?The duration of the headache,nausea and vomiting,neck stiffness in two groups were statistically significant(all P<0.05).The duration of those symptom in the experimental group was shorter than that of the control group.4?There was significant difference between the two groups in the number of analgesic drugs used in the course of treatment(P<0.05).The number of analgesic drugs used in the experimental group is less than that of the control group.5?There was no significant difference between the two groups(P>0.05)on the first day of the number of erythrocytes in cerebrospinal fluid.The number of erythrocytes in cerebrospinal fluid decreased on the 3rd,5th,7th,10 th and 14 th day in the two groups compared with the first day(all p <0.05).This shows that the number of erythrocytes in cerebrospinal fluid of two groups decreased compared with the previous after treatment.And there was a significant difference between the groups of cerebrospinal fluid erythrocytes on the 5th,7th,10 th,14th day.The decrease of erythrocyte number of cerebrospinal fluid in the experimental group was better than that of the control group.6?On the 7th day and the 14 th day after admission,the TCM symptom scores of the two groups were significantly lower than those of the first day after admission(P <0.05).The results showed that both TCM syndrome scores of the two groups were improved after treatment.And the TCM syndrome score of two groups on the 7th day,the 14 th days were statistically significant difference(P <0.05).And the TCM symptom scores of the experimental group were improved better than that of the control group.7?There was significant difference between the two groups in GOS score after treatment(P<0.05).And the GOS score of experimental group is better than the control group.8?After treatment,the adverse reaction rate was 5% in the experimental group and 10% in the control group.There was no statistically significant difference in the incidence of adverse reactions between the two groups(P>0.05),indicating no significant difference in the incidence of adverse reactions between the two groups.Conclusion:1.Xuefuzhuyu decoction orally and the ShouQingSan acupuncture sticking can effectively reduce the degree of aSAH patients with acute headache and reduce the duration of headache and reduce the use of analgesic drugs.2.Xuefuzhuyu decoction orally and the ShouQingSan acupuncture sticking can promote the removal of erythrocytes in cerebrospinal fluid,shorten the duration of nausea and vomiting,neck stiffness and other symptoms.3.Xuefuzhuyu decoction orally and the ShouQingSan acupuncture sticking can improve the patient's TCM Syndrome score and Glasgow prognostic score.